Photoreceptor cell death is the major hallmark of a group of human inherited retinal
degenerations commonly referred to as retinitis pigmentosa (RP). Although the causative genetic …

For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly
understood, a problem that is exacerbated by the enormous genetic heterogeneity of this …

Cell death in neurodegenerative diseases is often thought to be governed by apoptosis;
however, an increasing body of evidence suggests the involvement of alternative cell death …

Congenital absence of cone photoreceptor function is associated with strongly impaired
daylight vision and loss of color discrimination in human achromatopsia. Here, we introduce …

Purpose.: Spectral domain optical coherence tomography (SD-OCT) allows cross-sectional
visualization of retinal structures in vivo. Here, the authors report the efficacy of a …

Retinitis pigmentosa (RP) is an inherited blinding disease for which there is no treatment
available. It is characterized by a progressive and neurodegenerative loss of photoreceptors …

… models - Paquet‐Durand - 2009 - Journal of Neurochemistry - Wiley Online Library … pVASP
(f) is detected in all layers of the rd1 retina, including the ONL. Untreated wt retinal explants …

… n⩾3 for each time point and genotype, data for TUNEL assay were previously published
in Paquet-Durand et al., 2007 and are shown here for reference purposes only …

Calpain is activated in degenerating photoreceptors in the rd1 mouse - Paquet‐Durand - …
AB81013 antibodies showed equal levels of expression of the main 80-kDa protein at PN11 (F. …