Leishmania and the leishmaniases: a parasite genetic update and advances in taxonomy, epidemiology and pathogenicity in humans

AL Banuls, M Hide, F Prugnolle - Advances in parasitology, 2007 - Elsevier
Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

[HTML][HTML] Inferring sex-biased dispersal from population genetic tools: a review

F Prugnolle, T De Meeˆus - Heredity, 2002 - nature.com
F st estimates. The author has shown, in particular, that the ratios of sex-specific F st parameters
evaluated after dispersal over F … is the multilocus estimator of F xx st among individuals …

Antimicrobial resistance in wildlife

M Vittecoq, S Godreuil, F Prugnolle… - Journal of Applied …, 2016 - Wiley Online Library
The spread of antimicrobial resistance is of major concern for human health and leads to
growing economic costs. While it is increasingly hypothesized that wildlife could play an …

An African origin for the intimate association between humans and Helicobacter pylori

…, H Liu, P Roumagnac, D Falush, C Stamer, F Prugnolle… - Nature, 2007 - nature.com
… pylori and humans, except that F ST is considerably higher in H. pylori. … by Structure explains
70% of the variance of pairwise F ST for populations with 10 or more isolates, versus up to …

[HTML][HTML] Pathogen-driven selection and worldwide HLA class I diversity

F Prugnolle, A Manica, M Charpentier, JF Guégan… - Current biology, 2005 - cell.com
The human leukocyte antigen (HLA; known as MHC in other vertebrates) plays a central role
in the recognition and presentation of antigens to the immune system and represents the …

[HTML][HTML] Geography predicts neutral genetic diversity of human populations

F Prugnolle, A Manica, F Balloux - Current Biology, 2005 - cell.com
A leading theory for the origin of modern humans, the ‘recent African origin' (RAO) model [1],
postulates that the ancestors of all modern humans originated in East Africa and that, …

[PDF][PDF] A geographically explicit genetic model of worldwide human-settlement history

H Liu, F Prugnolle, A Manica, F Balloux - The American journal of human …, 2006 - cell.com
Currently available genetic and archaeological evidence is generally interpreted as supportive
of a recent single origin of modern humans in East Africa. However, this is where the near …

African great apes are natural hosts of multiple related malaria species, including Plasmodium falciparum

F Prugnolle, P Durand, C Neel… - Proceedings of the …, 2010 - National Acad Sciences
Plasmodium reichenowi, a chimpanzee parasite, was until very recently the only known
close relative of Plasmodium falciparum, the most virulent agent of human malaria. Recently, …

[HTML][HTML] Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

…, JW Barnwell, F Renaud, B Ollomo, F Prugnolle… - Nature, 2017 - nature.com
Elucidation of the evolutionary history and interrelatedness of Plasmodium species that
infect humans has been hampered by a lack of genetic information for three human-infective …

Population genetics and molecular epidemiology or how to “débusquer la bête”

T De Meeûs, KD McCoy, F Prugnolle… - Infection, Genetics and …, 2007 - Elsevier
… Assuming small values of m and replacing Q S by F ST we reach the classical formula:(12)
F ST ≈ 1 4 N m + 1 From this, the number of migrants can theoretically be estimated as N m …