A comprehensive concept of optogenetics
Fundamental questions that neuroscientists have previously approached with classical
biochemical and electrophysiological techniques can now be addressed using optogenetics. The …
biochemical and electrophysiological techniques can now be addressed using optogenetics. The …
[HTML][HTML] Principes et applications de l'optogénétique en neuroscience
GP Dugué, L Tricoire - médecine/sciences, 2015 - medecinesciences.org
Une grande partie des progrès de la biologie est indissociable de l’évolution de la
biophotonique, terme générique désignant l’utilisation de la lumière dans l’étude des systèmes …
biophotonique, terme générique désignant l’utilisation de la lumière dans l’étude des systèmes …
[HTML][HTML] Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network
Tonic motor control involves oscillatory synchronization of activity at low frequency (5–30 Hz)
throughout the sensorimotor system, including cerebellar areas. We investigated the …
throughout the sensorimotor system, including cerebellar areas. We investigated the …
Activity patterns of serotonin neurons underlying cognitive flexibility
10.7554/eLife.20552.001 Serotonin is implicated in mood and affective disorders. However,
growing evidence suggests that a core endogenous role is to promote flexible adaptation to …
growing evidence suggests that a core endogenous role is to promote flexible adaptation to …
[HTML][HTML] Balanced activity in basal ganglia projection pathways is critical for contraversive movements
The basal ganglia, and the striatum in particular, have been implicated in the generation of
contraversive movements. The striatum projects to downstream basal ganglia nuclei through …
contraversive movements. The striatum projects to downstream basal ganglia nuclei through …
Optical monitoring of neuronal activity at high frame rate with a digital random-access multiphoton (RAMP) microscope
Two-photon microscopy offers the promise of monitoring brain activity at multiple locations
within intact tissue. However, serial sampling of voxels has been difficult to reconcile with …
within intact tissue. However, serial sampling of voxels has been difficult to reconcile with …
A subcortical inhibitory signal for behavioral arrest in the thalamus
K Giber, MA Diana, VM Plattner, GP Dugué… - Nature …, 2015 - nature.com
Organization of behavior requires rapid coordination of brainstem and forebrain activity. The
exact mechanisms of effective communication between these regions are presently unclear. …
exact mechanisms of effective communication between these regions are presently unclear. …
Target-dependent use of coreleased inhibitory transmitters at central synapses
GP Dugué, A Dumoulin, A Triller… - Journal of …, 2005 - Soc Neuroscience
Corelease of GABA and glycine by mixed neurons is a prevalent mode of inhibitory transmission
in the vertebrate hindbrain. However, little is known of the functional organization of …
in the vertebrate hindbrain. However, little is known of the functional organization of …
Cerebellum involvement in cortical sensorimotor circuits for the control of voluntary movements
RD Proville, M Spolidoro, N Guyon, GP Dugué… - Nature …, 2014 - nature.com
Sensorimotor integration is crucial to perception and motor control. How and where this
process takes place in the brain is still largely unknown. Here we analyze the cerebellar …
process takes place in the brain is still largely unknown. Here we analyze the cerebellar …
Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge
Climbing fibers, the projections from the inferior olive to the cerebellar cortex, carry sensorimotor
error and clock signals that trigger motor learning by controlling cerebellar Purkinje cell …
error and clock signals that trigger motor learning by controlling cerebellar Purkinje cell …