Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections
HL Itell, A Kaur, JD Deere, PA Barry… - Current opinion in virology, 2017 - Elsevier
… Author links open overlay panel Hannah L Itell 1 , Amitinder Kaur 2 , Jesse D Deere 3 ,
Peter A Barry 3 , Sallie R Permar 1 4 … Eudailey, H. Heimsath, J. Himes, et al. …
Peter A Barry 3 , Sallie R Permar 1 4 … Eudailey, H. Heimsath, J. Himes, et al. …
Maternal immune correlates of protection against placental transmission of cytomegalovirus
Human cytomegalovirus (HCMV) is the most common congenitally transmitted pathogen
worldwide, impacting an estimated 1 million newborns annually. In a subset of infected infants, …
worldwide, impacting an estimated 1 million newborns annually. In a subset of infected infants, …
[PDF][PDF] Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs
A major goal of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope targets …
vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope targets …
[HTML][HTML] Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys
… Additionally, in comparison with the control group, the average number of days to first urine
shedding (G) and first saliva shedding (H) is increased in the high-potency HIG group (both P …
shedding (G) and first saliva shedding (H) is increased in the high-potency HIG group (both P …
[PDF][PDF] High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies
Defining long-term protective immunity to SARS-CoV-2 is one of the most pressing questions
of our time and will require a detailed understanding of potential ways this virus can evolve …
of our time and will require a detailed understanding of potential ways this virus can evolve …
[HTML][HTML] Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques
DR Ram, C Manickam, B Hueber, HL Itell… - PLoS …, 2018 - journals.plos.org
Natural killer (NK) cells classically typify the nonspecific effector arm of the innate immune
system, but have recently been shown to possess memory-like properties against multiple …
system, but have recently been shown to possess memory-like properties against multiple …
[PDF][PDF] CMV primes functional alternative signaling in adaptive Δg NK cells but is subverted by lentivirus infection in rhesus macaques
Despite burgeoning evidence demonstrating the adaptive properties of natural killer (NK)
cells, mechanistic data explaining these phenomena are lacking. Following antibody …
cells, mechanistic data explaining these phenomena are lacking. Following antibody …
[PDF][PDF] Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
HL Itell, D Humes, J Overbaugh - Cell reports, 2023 - cell.com
… For results from 6, 12, and 24 h post-IFN, we selected genes that were IFN stimulated by
at … Because we only had one donor with cells collected at 3 h post-IFN, we applied a more …
at … Because we only had one donor with cells collected at 3 h post-IFN, we applied a more …
[HTML][HTML] Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy
…, CA Lopez, C Giuberti, ML Dennis, HL Itell… - PLoS Neglected …, 2019 - journals.plos.org
… Plates were incubated for 20 minutes, upon which 1N H 2 SO 4 was added to stop the
reaction. A positive result required that the absorbance for a particular plasma was greater than 3-…
reaction. A positive result required that the absorbance for a particular plasma was greater than 3-…
SARS-CoV-2 antibody binding and neutralization in dried blood spot eluates and paired plasma
… All plasma specimens were heat inactivated at 56C for 1 h … ) nonfat milk in PBS-T for 1 h at
RT. Plasma and DBS eluates … assay plates were incubated for 2 h at RT. Wells were washed …
RT. Plasma and DBS eluates … assay plates were incubated for 2 h at RT. Wells were washed …