Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections

HL Itell, A Kaur, JD Deere, PA Barry… - Current opinion in virology, 2017 - Elsevier
… Author links open overlay panel Hannah L Itell 1 , Amitinder Kaur 2 , Jesse D Deere 3 ,
Peter A Barry 3 , Sallie R Permar 1 4 … Eudailey, H. Heimsath, J. Himes, et al. …

Maternal immune correlates of protection against placental transmission of cytomegalovirus

HL Itell, CS Nelson, DR Martinez, SR Permar - Placenta, 2017 - Elsevier
Human cytomegalovirus (HCMV) is the most common congenitally transmitted pathogen
worldwide, impacting an estimated 1 million newborns annually. In a subset of infected infants, …

[PDF][PDF] Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs

…, J Galloway, HY Chu, MM Shipley, K Sung, HL Itell… - Cell Reports, 2021 - cell.com
A major goal of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope targets …

[HTML][HTML] Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys

…, L Stamper, H Wu, M Gilbert, R Blair, X Alvarez, H Itell… - JCI insight, 2017 - ncbi.nlm.nih.gov
… Additionally, in comparison with the control group, the average number of days to first urine
shedding (G) and first saliva shedding (H) is increased in the high-potency HIG group (both P …

[PDF][PDF] High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies

ME Garrett, J Galloway, HY Chu, HL Itell, CI Stoddard… - Cell, 2021 - cell.com
Defining long-term protective immunity to SARS-CoV-2 is one of the most pressing questions
of our time and will require a detailed understanding of potential ways this virus can evolve …

[HTML][HTML] Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques

DR Ram, C Manickam, B Hueber, HL Itell… - PLoS …, 2018 - journals.plos.org
Natural killer (NK) cells classically typify the nonspecific effector arm of the innate immune
system, but have recently been shown to possess memory-like properties against multiple …

[PDF][PDF] CMV primes functional alternative signaling in adaptive Δg NK cells but is subverted by lentivirus infection in rhesus macaques

SV Shah, C Manickam, DR Ram, K Kroll, H Itell… - Cell reports, 2018 - cell.com
Despite burgeoning evidence demonstrating the adaptive properties of natural killer (NK)
cells, mechanistic data explaining these phenomena are lacking. Following antibody …

[PDF][PDF] Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells

HL Itell, D Humes, J Overbaugh - Cell reports, 2023 - cell.com
… For results from 6, 12, and 24 h post-IFN, we selected genes that were IFN stimulated by
at … Because we only had one donor with cells collected at 3 h post-IFN, we applied a more …

[HTML][HTML] Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy

…, CA Lopez, C Giuberti, ML Dennis, HL Itell… - PLoS Neglected …, 2019 - journals.plos.org
… Plates were incubated for 20 minutes, upon which 1N H 2 SO 4 was added to stop the
reaction. A positive result required that the absorbance for a particular plasma was greater than 3-…

SARS-CoV-2 antibody binding and neutralization in dried blood spot eluates and paired plasma

HL Itell, H Weight, CS Fish, JK Logue… - Microbiology …, 2021 - Am Soc Microbiol
… All plasma specimens were heat inactivated at 56C for 1 h … ) nonfat milk in PBS-T for 1 h at
RT. Plasma and DBS eluates … assay plates were incubated for 2 h at RT. Wells were washed …