Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFα and IL‐1α

H Torisu, M Ono, H Kiryu, M Furue… - … journal of cancer, 2000 - Wiley Online Library
We examined whether macrophage infiltration is associated with angiogenesis in cutaneous
melanoma. The numbers of macrophages and microvessels increased significantly with …

SCODE: an efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation

H Matsumoto, H Kiryu, C Furusawa, MSH Ko… - …, 2017 - academic.oup.com
… For each set of dynamics, the initial values ( x at t = 0) were set to the mean expression of
0-h or day 0 cells. At first, we compared the reconstructed dynamics with observed data in the …

Encapsulated fat necrosis–a clinicopathological study of 8 cases and a literature review

H Kiryu, W Rikihisa, M Furue - Journal of cutaneous pathology, 2000 - Wiley Online Library
… Hiromaro Kiryu, Wataru Rikihisa were two males and six females from 10 to 77 years of age.
… Hiromaro Kiryu, MD, Department of based on the clinical and histological findings of the …

Prediction of RNA secondary structure using generalized centroid estimators

M Hamada, H Kiryu, K Sato, T Mituyama, K Asai - Bioinformatics, 2009 - academic.oup.com
Motivation: Recent studies have shown that the methods for predicting secondary structures
of RNAs on the basis of posterior decoding of the base-pairing probabilities has an …

Prurigo pigmentosa: a distinctive inflammatory disease of the skin

A Böer, N Misago, M Wolter, H Kiryu… - The American journal …, 2003 - journals.lww.com
More than 200 patients with prurigo pigmentosa, a disease described first by Nagashima in
1971, have been reported on in Japan, but only 28 non-Japanese patients have come to …

[HTML][HTML] A fast structural multiple alignment method for long RNA sequences

Y Tabei, H Kiryu, T Kin, K Asai - BMC bioinformatics, 2008 - Springer
Kiryu et al. proposed a variant of Sankoff's algorithm with marked reduction of computation,
which was implemented in Murlet [21]. All of these methods, however, are still too slow to …

[HTML][HTML] CapR: revealing structural specificities of RNA-binding protein target recognition using CLIP-seq data

…, H Ozaki, G Terai, K Asai, W Iwasaki, H Kiryu - Genome biology, 2014 - Springer
… The probability p(i,δ) that a base at position i has the structural context δ∈{B,E,H,I,M,S} is …
Although Kiryu et al. revealed the dependence of the accessibilities on the GC content [12], the …

[HTML][HTML] SCOUP: a probabilistic model based on the Ornstein–Uhlenbeck process to analyze single-cell expression data during differentiation

H Matsumoto, H Kiryu - BMC bioinformatics, 2016 - Springer
… in mean gene expression between the 1-h cells and 6-h cells for each stimulation. We … ,
and PIC data and regarded these cells as 0-h data. The initial distribution was calculated from …

A detailed investigation of accessibilities around target sites of siRNAs and miRNAs

H Kiryu, G Terai, O Imamura, H Yoneyama… - …, 2011 - academic.oup.com
… Symbol ‘–’ indicates that the program does not return results within 10 h. Symbol ‘x’ indicates
that the program terminates within 10 h but does not return any result due to overflow errors…

Murlet: a practical multiple alignment tool for structural RNA sequences

H Kiryu, Y Tabei, T Kin, K Asai - Bioinformatics, 2007 - academic.oup.com
Motivation: Structural RNA genes exhibit unique evolutionary patterns that are designed to
conserve their secondary structures; these patterns should be taken into account while …