[HTML][HTML] Genomic diversity of bacteriophages infecting Microbacterium spp

…, JAL Whitefleet-Smith, HI Wiersma-Koch… - PLoS …, 2020 - journals.plos.org
The bacteriophage population is vast, dynamic, old, and genetically diverse. The genomics
of phages that infect bacterial hosts in the phylum Actinobacteria show them to not only be …

Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community

…, MF Poelchau, JB Benoit, H Wiersma-Koch… - Database, 2017 - academic.oup.com
The Asian citrus psyllid (Diaphorina citri Kuwayama) is the insect vector of the bacterium
Candidatus Liberibacter asiaticus (CLas), the pathogen associated with citrus Huanglongbing (…

High-resolution analysis of Zn2+ coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography

E Bobyr, JK Lassila, HI Wiersma-Koch, TD Fenn… - Journal of molecular …, 2012 - Elsevier
Comparisons among evolutionarily related enzymes offer opportunities to reveal how
structural differences produce different catalytic activities. Two structurally related enzymes, …

Mechanistic and evolutionary insights from comparative enzymology of phosphomonoesterases and phosphodiesterases across the alkaline phosphatase …

…, AY Lyubimov, S Ressl, H Wiersma-Koch… - Journal of the …, 2016 - ACS Publications
Naively one might have expected an early division between phosphate monoesterases and
diesterases of the alkaline phosphatase (AP) superfamily. On the contrary, prior results and …

[HTML][HTML] A quick guide for student-driven community genome annotation

…, LA Mueller, H Wiersma-Koch… - PLoS computational …, 2019 - journals.plos.org
High quality gene models are necessary to expand the molecular and genetic tools available
for a target organism, but these are available for only a handful of model organisms that …

Site-directed mutagenesis maps interactions that enhance cognate and limit promiscuous catalysis by an alkaline phosphatase superfamily phosphodiesterase

H Wiersma-Koch, F Sunden, D Herschlag - Biochemistry, 2013 - ACS Publications
Catalytic promiscuity, an evolutionary concept, also provides a powerful tool for gaining
mechanistic insights into enzymatic reactions. Members of the alkaline phosphatase (AP) …

Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community

…, MF Poelchau, JB Benoit, H Wiersma-Koch… - Database, 2019 - academic.oup.com
… Surya Saha, Prashant S Hosmani, Krystal Villalobos-Ayala, Sherry Miller, Teresa Shippy,
Mirella Flores, Andrew Rosendale, Chris Cordola, Tracey Bell, Hannah Mann, Gabe DeAvila …

Complete genome sequence of Xanthomonas phage RiverRider, a novel N4-like bacteriophage that infects the strawberry pathogen Xanthomonas fragariae

…, C Holland, C Douthitt, J McMahon, H Wiersma-Koch… - Archives of …, 2020 - Springer
Xanthomonas phage RiverRider is a novel N4-like bacteriophage and the first phage
isolated from the plant pathogen Xanthomonas fragariae. Electron microscopy revealed a …

[BOOK][B] Catalytic Promiscuity in the Alkaline Phosphatase Superfamily: Identifying Specificity Determinants in the Diesterase Family Leads to a Hypothesis of a" …

HI Wiersma-Koch - 2013 - search.proquest.com
Catalytic promiscuity, the property of enzymes possessing low levels of activity toward non-cognate
reactions, can be exploited as a functional tool to investigate conserved and non-…

[PDF][PDF] Improved annotation of the insect vector of Citrus greening disease: Biocuration by a diverse genomics community

…, D Nelson, MF Poelchau, JB Benoit, H Wiersma-Koch… - researchgate.net
The Asian citrus psyllid (Diaphorina citri Kuwayama) is the insect vector of the bacterium
Candidatus Liberibacter asiaticus (CLas), the pathogen associated with citrus Huanglongbing (…