A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic …
Objective Gastric cancer is a major gastrointestinal malignancy for which targeted therapies
are emerging as treatment options. This study sought to identify the most prevalent …
are emerging as treatment options. This study sought to identify the most prevalent …
Is photodynamic therapy a good alternative to surgery and radiotherapy in the treatment of head and neck cancer?
HJ Nyst, IB Tan, FA Stewart, AJM Balm - Photodiagnosis and photodynamic …, 2009 - Elsevier
The mainstay treatments for head and neck carcinomas are surgery, radiotherapy and
chemotherapy. These treatment options may be associated with considerable complications. …
chemotherapy. These treatment options may be associated with considerable complications. …
Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates
Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving
to be effective at restoring T cell-mediated immune responses that can lead to marked and …
to be effective at restoring T cell-mediated immune responses that can lead to marked and …
Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors
Intratumoral heterogeneity is a major obstacle to cancer treatment and a significant
confounding factor in bulk-tumor profiling. We performed an unbiased analysis of transcriptional …
confounding factor in bulk-tumor profiling. We performed an unbiased analysis of transcriptional …
Testicular microlithiasis predicts concurrent testicular germ cell tumors and intratubular germ cell neoplasia of unclassified type in adults: A meta‐analysis and …
IB Tan, KK Ang, BC Ching, C Mohan, CK Toh… - Cancer, 2010 - Wiley Online Library
Testicular microlithiasis predicts concurrent testicular germ cell tumors and intratubular germ
cell neoplasia of unclassified type in adults - Tan - 2010 - Cancer - Wiley Online Library …
cell neoplasia of unclassified type in adults - Tan - 2010 - Cancer - Wiley Online Library …
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
Gastric cancer is a major cause of global cancer mortality. We surveyed the spectrum of
somatic alterations in gastric cancer by sequencing the exomes of 15 gastric adenocarcinomas …
somatic alterations in gastric cancer by sequencing the exomes of 15 gastric adenocarcinomas …
[HTML][HTML] Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer
The consensus molecular subtype (CMS) classification of colorectal cancer is based on
bulk transcriptomics. The underlying epithelial cell diversity remains unclear. We analyzed …
bulk transcriptomics. The underlying epithelial cell diversity remains unclear. We analyzed …
[HTML][HTML] Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by …
The most recent version of the European Society for Medical Oncology (ESMO) consensus
guidelines for the treatment of patients with metastatic colorectal cancer (mCRC) was …
guidelines for the treatment of patients with metastatic colorectal cancer (mCRC) was …
[HTML][HTML] Nasopharyngeal carcinoma in Indonesia: epidemiology, incidence, signs, and symptoms at presentation
…, B Hermani, S Gondhowiardjo, IB Tan… - Chinese journal of …, 2012 - ncbi.nlm.nih.gov
Among all head and neck (H&N) cancers, nasopharyngeal carcinoma (NPC) represents a
distinct entity regarding epidemiology, clinical presentation, biological markers, carcinogenic …
distinct entity regarding epidemiology, clinical presentation, biological markers, carcinogenic …
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil
Background & Aims Almost all gastric cancers are adenocarcinomas, which have
considerable heterogeneity among patients. We sought to identify subtypes of gastric …
considerable heterogeneity among patients. We sought to identify subtypes of gastric …