Endogenous cardiotonic steroids (CTS), also called digitalis-like factors, have been postulated
to play important roles in health and disease for nearly half a century. Recent discoveries, …

Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …

Aging and cancer are the most important issues to research. The population in the world is
growing older, and the incidence of cancer increases with age. There is no doubt about the …

Background The availability of multiple, essentially complete genome sequences of prokaryotes
and eukaryotes spurred both the demand and the opportunity for the construction of an …

The database of Clusters of Orthologous Groups of proteins (COGs), which represents an
attempt on a phylogenetic classification of the proteins encoded in complete genomes, …

Aspergillus fumigatus is exceptional among microorganisms in being both a primary and
opportunistic pathogen as well as a major allergen 1 , 2 , 3 . Its conidia production is prolific, …

The genome of Aspergillus oryzae, a fungus important for the production of traditional
fermented foods and beverages in Japan, has been sequenced. The ability to secrete large …

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

Inhibitor of apoptosis (IAP) proteins are antiapoptotic regulators that block cell death in
response to diverse stimuli. They are expressed at elevated levels in human malignancies and …

The High Resolution Fly’s Eye (HiRes) experiment has observed the Greisen-Zatsepin-Kuzmin
suppression (called the GZK cutoff) with a statistical significance of five standard …