User profiles for I. Sharakhov

Igor Sharakhov

Virginia Tech
Verified email at vt.edu
Cited by 5209

Extensive introgression in a malaria vector species complex revealed by phylogenomics

…, A Steele, RM Waterhouse, DE Neafsey, IV Sharakhov… - Science, 2015 - science.org
Introduction The notion that species boundaries can be porous to introgression is increasingly
accepted. Yet the broader role of introgression in evolution remains contentious and …

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

…, JM Ribeiro, MA Riehle, IV Sharakhov… - Science, 2015 - science.org
INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …

[HTML][HTML] Improved reference genome of Aedes aegypti informs arbovirus vector control

…, TD Murphy, AS Raikhel, DB Sattelle, IV Sharakhov… - Nature, 2018 - nature.com
Female Aedes aegypti mosquitoes infect more than 400 million people each year with
dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress in …

A male-determining factor in the mosquito Aedes aegypti

…, R Elahi, MAE Anderson, XG Chen, IV Sharakhov… - Science, 2015 - science.org
Sex determination in the mosquito Aedes aegypti is governed by a dominant male-determining
factor (M factor) located within a Y chromosome–like region called the M locus. Here, we …

[HTML][HTML] Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi

…, K Michel, MA Riehle, S Luckhart, IV Sharakhov… - Genome biology, 2014 - Springer
Background Anopheles stephensi is the key vector of malaria throughout the Indian subcontinent
and Middle East and an emerging model for molecular and genetic studies of mosquito-…

Heterochromatin, histone modifications, and nuclear architecture in disease vectors

IV Sharakhov, MV Sharakhova - Current opinion in insect science, 2015 - Elsevier
… Author links open overlay panel Igor V Sharakhov 1 , Maria V Sharakhova 1 2 … George,
IV Brusentsova, SC Leman, JA Bailey, CD Smith, IV Sharakhov … IV Sharakhov

Release of mitotic descendants by giant cells from irradiated Burkitt's lymphoma cell lines

JA Erenpreisa, MS Cragg, B Fringes, I Sharakhov… - Cell biology …, 2000 - Elsevier
Polyploid giant cells are produced as part of the response of p53 mutant Burkitt's lymphoma
cell lines to high doses of irradiation. Polyploid giant cells arise by endo-reduplication in the …

[HTML][HTML] Six novel Y chromosome genes in Anophelesmosquitoes discovered by independently sequencing males and females

…, Y Qi, V Timoshevskiy, MV Sharakhova, IV Sharakhov… - BMC genomics, 2013 - Springer
Background Y chromosomes are responsible for the initiation of male development, male
fertility, and other male-related functions in diverse species. However, Y genes are rarely …

Breakpoint structure reveals the unique origin of an interspecific chromosomal inversion (2La) in the Anopheles gambiae complex

IV Sharakhov, BJ White… - Proceedings of the …, 2006 - National Acad Sciences
Paracentric chromosomal inversions are major architects of organismal evolution and have
been associated with adaptations relevant to malaria transmission in anopheline mosquitoes…

Genus-wide characterization of bumblebee genomes provides insights into their evolution and variation in ecological and behavioral traits

…, M Kellis, S Vicario, IV Sharakhov… - Molecular biology …, 2021 - academic.oup.com
Bumblebees are a diverse group of globally important pollinators in natural ecosystems and
for agricultural food production. With both eusocial and solitary life-cycle phases, and some …