Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

Background During the recent H1N1 influenza pandemic, excess morbidity and mortality was
seen in young but not older adults suggesting that prior infection with influenza strains may …

Background Zika virus (ZIKV; Flaviviridae, Flavivirus) was declared a public health emergency
of international concern by the World Health Organization (WHO) in February 2016, …

Most antibodies that broadly neutralize HIV-1 are highly somatically mutated in antibody
clonal lineages that persist over time. Here, we describe the analysis of human antibodies …

Congenital Zika virus (ZIKV) infection results in neurodevelopmental deficits in up to 14% of
infants born to ZIKV-infected mothers. Neutralizing antibodies are a critical component of …

Huntington's disease (HD) is a late-onset, neurodegenerative disease for which there are
currently no cures nor disease-modifying treatments. Here we report the identification of …

Interactions between innate antiviral factors at mucosal surfaces and HIV-1 virions
contribute to the natural inefficiency of HIV-1 transmission and are a platform to inform the …

Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-reactive
IgG antibodies against related flaviviruses, which shapes subsequent protection or …

Despite the risk of transmitting HIV-1, mothers in resource-poor areas are encouraged to
breastfeed their infants because of beneficial immunologic and nutritional factors in milk. …