Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …

In recent years, mass violence associated with men who identify as involuntary celibates (incels)
has been of increasing concern. Incels engage in an online community where …

Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …

Accessibility of powerful computers and availability of so-called big data from a variety of
sources means that data science approaches are becoming pervasive. However, their …

Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale
genome-wide association studies (GWASs) recently discovered and cross-validated …

Objectives Researchers need to be confident about the reliability of epidemiologic studies
that quantify medication use through self-report. Some evidence suggests that psychiatric …

Importance Suicide is a leading cause of death; however, the molecular genetic basis of
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel, replicable …

DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of
genetic, stochastic, and environmental influences associated with aggression. Here, we …

Antidepressants demonstrate modest response rates in the treatment of major depressive
disorder (MDD). Despite previous genome-wide association studies (GWAS) of antidepressant …

STratifying Resilience and Depression Longitudinally (STRADL) is a population-based study
built on the Generation Scotland: Scottish Family Health Study (GS: SFHS) resource. The …