… (JD Jentsch, EJ Nestler and JR Taylor, unpublished observations). We have so far provided
two separate, but related, mechanisms by which chronic drugs of abuse can affect the neural …

… this is attributable to a simple sensitization phenomenon, because the locomotor
response to PCP itself is reduced after the drug administration regimen used in our studies (Jentsch …

Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains. …

The effects of the psychotomimetic drug phencyclidine on the neurochemistry and function
of the prefrontal cortex in vervet monkeys were investigated. Monkeys treated with …

… David Jentsch,3,4 Paul W. Frankland,1,2,3,4,… Jentsch, JD (2003). Genetic vasopressin
deficiency facilitates performance of a lateralized reaction-time task: altered attention and motor …

BACKGROUND: As a test of plausibility for the hypothesis that schizophrenia can result from
abnormal brain, especially cerebral cortical, development, these studies examined whether, …

Repeated ingestion of phencyclidine by humans induces enduring schizophrenic symptomatology,
particularly cognitive dysfunction. In the presently described series of experiments, …

Background Our ability to measure the cognitive components of complex decision-making
across species has greatly facilitated our understanding of its neurobiological mechanisms. …

The current experiments examined the effects of acute or repeated, intermittent administrations
of cocaine on the acquisition and reversal of object discriminations by Vervet monkeys in …

Drug use disorders are often accompanied by deficits in the capacity to efficiently process
reward‐related information and to monitor, suppress, or override reward‐controlled behavior …