User profiles for J. F. Dubern

Jean Dubern

Research Fellow
Verified email at nottingham.ac.uk
Cited by 1688

Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species

JF Dubern, SP Diggle - Molecular Biosystems, 2008 - pubs.rsc.org
Pseudomonas aeruginosa produces the cell-to-cell signal molecule 2-heptyl-3-hydroxy-4-quinolone
(The Pseudomonasquinolonesignal; PQS), which is integrated within a complicated …

Simultaneous quantitative profiling of N-acyl-l-homoserine lactone and 2-alkyl-4(1H)-quinolone families of quorum-sensing signaling molecules using LC-MS/MS

CA Ortori, JF Dubern, SR Chhabra, M Cámara… - Analytical and …, 2011 - Springer
An LC-MS/MS method, using positive mode electrospray ionization, for the simultaneous,
quantitative and targeted profiling of the N-acyl-l-homoserine lactone (AHL) and 2-alkyl 4-(1H)-…

[HTML][HTML] Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa

…, S Heeb, E Frangipani, MP Fletcher, JF Dubern… - PLoS …, 2016 - journals.plos.org
The pqs quorum sensing (QS) system is crucial for Pseudomonas aeruginosa virulence
both in vitro and in animal models of infection and is considered an ideal target for the …

The ppuI-rsaL-ppuR Quorum-Sensing System Regulates Biofilm Formation of Pseudomonas putida PCL1445 by Controlling Biosynthesis of the Cyclic Lipopeptides …

JF Dubern, BJJ Lugtenberg… - Journal of …, 2006 - Am Soc Microbiol
Pseudomonas putida strain PCL1445 produces two cyclic lipopeptides, putisolvin I and
putisolvin II, which possess surface tension-reducing abilities and are able to inhibit biofilm …

AbaM Regulates Quorum Sensing, Biofilm Formation, and Virulence in Acinetobacter baumannii

M López-Martín, JF Dubern, MR Alexander… - Journal of …, 2021 - Am Soc Microbiol
Acinetobacter baumannii possesses a single divergent luxR/luxRI-type quorum-sensing (QS)
locus named abaR/abaI. This locus also contains a third gene located between abaR and …

Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation

JF Dubern, AL Hook, AM Carabelli, CY Chang… - Science …, 2023 - science.org
Innovative approaches to prevent catheter-associated urinary tract infections (CAUTIs) are
urgently required. Here, we describe the discovery of an acrylate copolymer capable of …

The Heat Shock Genes dnaK, dnaJ, and grpE Are Involved in Regulation of Putisolvin Biosynthesis in Pseudomonas putida PCL1445

JF Dubern, EL Lagendijk, BJJ Lugtenberg… - Journal of …, 2005 - Am Soc Microbiol
Pseudomonas putida PCL1445 produces two cyclic lipopeptides, putisolvins I and II, which
possess surfactant activity and play an important role in biofilm formation and degradation. In …

[HTML][HTML] In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

F Soukarieh, E Vico Oton, JF Dubern, J Gomes… - Molecules, 2018 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis, wound and
nosocomial infections, posing a serious burden to public health, due to its antibiotic resistance. …

Integrated whole‐genome screening for Pseudomonas aeruginosa virulence genes using multiple disease models reveals that pathogenicity is host specific

JF Dubern, C Cigana, M De Simone… - Environmental …, 2015 - Wiley Online Library
Integrated whole‐genome screening for Pseudomonas aeruginosa virulence genes using
multiple disease models reveals that pathogenicity is host specific - Dubern - 2015 - …

Validating a predictive structure–property relationship by discovery of novel polymers which reduce bacterial biofilm formation

AA Dundas, O Sanni, JF Dubern… - Advanced …, 2019 - Wiley Online Library
Synthetic materials are an everyday component of modern healthcare yet often fail routinely
as a consequence of medical‐device‐centered infections. The incidence rate for catheter‐…