… Author links open overlay panel JM Ramírez a b , JM Andreu a c … (>0.35) internally
consistent and relatively independent of one another (Ramirez and Andreu, unpublished results). …

Microtubules are highly dynamic cellular polymers made of αβ-tubulin and associated proteins.
They play a key role during mitosis, participating in the exact organization and function of …

FtsZ is the key protein of bacterial cell division and an emergent target for new antibiotics. It
is a filament-forming GTPase and a structural homologue of eukaryotic tubulin. A number of …

… The taxolinduced microtubule assembly of tubulin has also beenshown to be maximal at
equimolarligand concentrations by X-ray solution scattering under the same conditions (Andreu …

Small-angle x-ray solution scattering (SAXS) is analyzed with a new method to retrieve
convergent model structures that fit the scattering profiles. An arbitrary hexagonal packing of …

Laulimalide is a cytotoxic natural product that stabilizes microtubules. The compound enhances
tubulin assembly, and laulimalide is quantitatively comparable to paclitaxel in its effects …

The recent success of antibody–drug conjugates (ADCs) in the treatment of cancer has led
to a revived interest in microtubule-destabilizing agents. Here, we determined the high-…

Two self‐report inventories developed to assess different dimensions of aggression, the
Aggression Questionnaire and the EXPAGG, were administered to a sample (N = 400) of men …

RL5, a gene coding for a novel polyphenol oxidase, was identified through activity screening
of a metagenome expression library from bovine rumen microflora. Characterization of the …

The interactions of microtubules with most compounds described as stabilizing agents have
been studied. Several of them (lonafarnib, dicumarol, lutein, and jatrophane polyesters) did …