User profiles for J. R. Unruh

Jay R. Unruh

Stowers Institute for Medical Research
Verified email at stowers.org
Cited by 6470

Integrative structure and functional anatomy of a nuclear pore complex

…, AS Chaudhury, J Wang, R Williams, JR Unruh… - Nature, 2018 - nature.com
Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport
between the cytoplasm and nucleoplasm. However, their large size and dynamic nature have …

Analysis of fault slip inversions: Do they constrain stress or strain rate?

RJ Twiss, JR Unruh - Journal of Geophysical Research: Solid …, 1998 - Wiley Online Library
… The particular grid search procedure and the definition of the misfit that we minimize are
described by Unruh et at. [1996]. In many cases, inversion based on the micropolar model gives …

The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration

P Suraneni, B Rubinstein, JR Unruh, M Durnin… - Journal of Cell …, 2012 - rupress.org
The Arp2/3 complex nucleates the formation of the dendritic actin network at the leading edge
of motile cells, but it is still unclear if the Arp2/3 complex plays a critical role in lamellipodia …

Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes

K Yi, JR Unruh, M Deng, BD Slaughter… - Nature cell …, 2011 - nature.com
Mature mammalian oocytes are poised for completing meiosis II (MII) on fertilization by
positioning the spindle close to an actomyosin-rich cortical cap 1 , 2 , 3 . Here, we show that the …

[PDF][PDF] Organelle-based aggregation and retention of damaged proteins in asymmetrically dividing cells

C Zhou, BD Slaughter, JR Unruh, F Guo, Z Yu… - Cell, 2014 - cell.com
Aggregation of damaged or misfolded proteins is a protective mechanism against proteotoxic
stress, abnormalities of which underlie many aging-related diseases. Here, we show that in …

The role of gravitational potential energy in active deformation in the southwestern United States

CH Jones, JR Unruh, LJ Sonder - Nature, 1996 - nature.com
In orogenic belts, intrinsic (buoyancy) and extrinsic (boundary) forces act on the continental
lithosphere; determining the relative importance of these forces is fundamental to …

DNA aptamer-based bioanalysis of IgE by fluorescence anisotropy

G Gokulrangan, JR Unruh, DF Holub, B Ingram… - Analytical …, 2005 - ACS Publications
A rapid, homogeneous aptamer-based bioanalysis is reported for the sensitive detection of
immunoglobulin E (IgE) using fluorescence polarization (FP). 5‘-End-labeled D17.4 DNA …

[PDF][PDF] Actin depolymerization drives actomyosin ring contraction during budding yeast cytokinesis

IM Pinto, B Rubinstein, A Kucharavy, JR Unruh, R Li - Developmental cell, 2012 - cell.com
Actin filaments and myosin II are evolutionarily conserved force-generating components of
the contractile ring during cytokinesis. Here we show that in budding yeast, actin filament …

The uplift of the Sierra Nevada and implications for late Cenozoic epeirogeny in the western Cordillera

JR Unruh - Geological Society of America Bulletin, 1991 - pubs.geoscienceworld.org
Tilted Cenozoic strata in the eastern Great Valley, California, record progressive late Cenozoic
uplift of the Sierra Nevada. The magnitude of tilting is combined with other geologic data, …

[HTML][HTML] Motility and segregation of Hsp104-associated protein aggregates in budding yeast

C Zhou, BD Slaughter, JR Unruh, A Eldakak… - Cell, 2011 - cell.com
During yeast cell division, aggregates of damaged proteins are segregated asymmetrically
between the bud and the mother. It is thought that protein aggregates are cleared from the …