INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …

Batrachochytrium dendrobatidis is a pathogen of amphibians that has been implicated in
severe population declines on several continents. We investigated the zoospore activity, …

• Arbuscular mycorrhizal fungi (AMF) and roots mediate soil stabilization, although the
mechanisms and how their interactions affect soil stabilization are not known. We tested the …

New antifungal drugs are urgently needed to address the emergence and transcontinental
spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging …

Advances in genomics and metabolomics have made clear in recent years that microbial
biosynthetic capacities on Earth far exceed previous expectations. This is attributable, in part, to …

The lack of disease-modifying treatments for neurodegenerative disease stems in part from
our rudimentary understanding of disease mechanisms and the paucity of targets for …

Forazoline A, a novel antifungal polyketide with in vivo efficacy against Candida albicans,
was discovered using LCMS‐based metabolomics to investigate marine‐invertebrate‐…

A rise in resistance to current antifungals necessitates strategies to identify alternative
sources of effective fungicides. We report the discovery of poacic acid, a potent antifungal …

Sclerotinia sclerotiorum, a predominately necrotrophic fungal pathogen with a broad host
range, causes a significant yield‐limiting disease of soybean called Sclerotinia stem rot. …

Lignocellulosic hydrolysate (LCH) inhibitors are a large class of bioactive molecules that
arise from pretreatment, hydrolysis, and fermentation of plant biomass. These diverse …