The mammalian gut is a dynamic community of symbiotic microbes that interact with the host
to impact health, disease, and metabolism. We constructed engineered bacteria that survive …

Bacteria can be engineered to function as diagnostics or therapeutics in the mammalian gut
but commercial translation of technologies to accomplish this has been hindered by the …

The intestine is a major source of systemic ammonia (NH 3 ); thus, capturing part of gut NH
3 may mitigate disease symptoms in conditions of hyperammonemia such as urea cycle …

To reduce the adverse effects of cancer therapies and increase their efficacy, new delivery
agents that specifically target cancer cells are needed. We and others have shown that …

Microbial population growth is typically measured when cells can be directly observed, or
when death is rare. However, neither of these conditions hold for the mammalian gut …

<p>β-arrestins, ubiquitous cellular scaffolding proteins that act as signaling mediators of
numerous critical cellular pathways, are attractive therapeutic targets because they promote …

Inflammation in the gut, caused by infection and autoimmunity, remains challenging to
effectively detect, monitor, and treat. Here, we engineer a commensal mouse E. coli strain to …

Advances in antibody and aptamer technology have enabled researchers to design those
molecules to bind specifically to cancer cells, and deliver drugs that alter specific cellular …

In a companion paper, fluorescence lifetime imaging revealed a heterogeneous morphology
at macroscopic and molecular length scales in a bis-epoxide blend composed of diglycidyl …

The rheology of crystallizing polymers is critical to polymer processing, but our current
understanding of how crystallinity affects rheology during crystallization is lacking. The challenge …