Core outcome measures for chronic pain clinical trials: IMMPACT recommendations

RH Dworkin, DC Turk, JT Farrar, JA Haythornthwaite… - Pain, 2005 - journals.lww.com
… Cleeland, PhD, for his comments on a preliminary draft of this article, and Paul J. Lambiase
and Mary Gleichauf for their invaluable assistance. Abbott Laboratories, AstraZeneca, Elan …

[HTML][HTML] Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations

…, KW Wyrwich, D Beaton, CS Cleeland, JT Farrar… - The journal of pain, 2008 - Elsevier
A consensus meeting was convened by the Initiative on Methods, Measurement, and Pain
Assessment in Clinical Trials (IMMPACT) to provide recommendations for interpreting clinical …

[HTML][HTML] Dengue: a continuing global threat

…, SB Halstead, H Artsob, P Buchy, J Farrar… - Nature reviews …, 2010 - nature.com
Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases.
Each year, there are ∼50 million dengue infections and ∼500,000 individuals are …

The global distribution and burden of dengue

…, GRW Wint, CP Simmons, TW Scott, JJ Farrar… - Nature, 2013 - nature.com
Dengue is a systemic viral infection transmitted between humans by Aedes mosquitoes 1 .
For some patients, dengue is a life-threatening illness 2 . There are currently no licensed …

Herbivory in global climate change research: direct effects of rising temperature on insect herbivores

…, J Butterfield, A Buse, JC Coulson, J Farrar… - Global change …, 2002 - Wiley Online Library
This review examines the direct effects of climate change on insect herbivores. Temperature
is identified as the dominant abiotic factor directly affecting herbivorous insects. There is …

Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale

JT Farrar, JP Young Jr, L LaMoreaux, JL Werth… - Pain, 2001 - Elsevier
Pain intensity is frequently measured on an 11-point pain intensity numerical rating scale (PI-NRS),
where 0=no pain and 10=worst possible pain. However, it is difficult to interpret the …

Pharmacologic management of neuropathic pain: evidence-based recommendations

RH Dworkin, AB O'connor, M Backonja, JT Farrar… - Pain, 2007 - Elsevier
Patients with neuropathic pain (NP) are challenging to manage and evidence-based clinical
recommendations for pharmacologic management are needed. Systematic literature …

Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

…, P Davis, RM Davies, L Dowd, N White, J Farrar… - Nature, 2001 - nature.com
Salmonella enterica serovar Typhi (S. typhi) is the aetiological agent of typhoid fever, a serious
invasive bacterial disease of humans with an annual global burden of approximately 16 …

[HTML][HTML] Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

…, Y Guan, JSM Peiris, NT Chinh, TT Hien, J Farrar - Nature medicine, 2006 - nature.com
Avian influenza A (H5N1) viruses cause severe disease in humans 1 , 2 , but the basis for
their virulence remains unclear. In vitro and animal studies indicate that high and …

Into the eye of the cytokine storm

…, MJ Korth, CP Simmons, J Farrar… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community alike,
and while the general notion of an excessive or uncontrolled release of proinflammatory …