Increasing public interest in direct-to-consumer (DTC) genetic ancestry testing has been
accompanied by growing concern about issues ranging from the personal and societal …

Conservation practitioners have long recognized ecological connectivity as a global priority
for preserving biodiversity and ecosystem function. In the early years of conservation science…

Empowered by technology and sampling efforts designed to facilitate genome-wide
association mapping, human geneticists are now studying the geography of genetic variation in …

Rare genetic variants contribute to complex disease risk; however, the abundance of rare
variants in human populations remains unknown. We explored this spectrum of variation by …

Advances in genome technology have facilitated a new understanding of the historical and
genetic processes crucial to rapid phenotypic evolution under domestication 1 , 2 . To …

… This work was supported by a Packard Foundation grant to J. Pritchard. J. Pickrell was
supported by an NIH training grant to the University of Chicago. JN was supported by a US …

Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body
size than any other terrestrial mammal. Here, we generate a high density map of canine …

… Funding: This work was supported by a Packard Foundation grant to J. Pritchard. J. Pickrell
was supported by a National Institutes of Health training grant to the University of Chicago. G. …

Ancient genomic sequences have started to reveal the origin and the demographic impact
of farmers from the Neolithic period spreading into Europe 1 , 2 , 3 . The adoption of farming, …

Background Genomewide association studies of autoimmune diseases have mapped hundreds
of susceptibility regions in the genome. However, only for a few association signals has …