User profiles for J. Rolff

Jens Rolff

Freie Universität Berlin
Verified email at fu-berlin.de
Cited by 7924

Invertebrate ecological immunology

J Rolff, MT Siva-Jothy - Science, 2003 - science.org
Ecological immunology is a rapidly expanding field that examines the causes and consequences
of variation in immune function in the context of evolution and of ecology. Millions of …

Priming and memory of stress responses in organisms lacking a nervous system

…, B Mueller‐Roeber, MC Rillig, J Rolff… - Biological …, 2016 - Wiley Online Library
Experience and memory of environmental stimuli that indicate future stress can prepare (prime)
organismic stress responses even in species lacking a nervous system. The process …

Antimicrobial peptides: Application informed by evolution

BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …

Bateman's principle and immunity

J Rolff - Proceedings of the Royal Society of London …, 2002 - royalsocietypublishing.org
The immunocompetence handicap hypothesis (ICHH) of Folstad and Karter has inspired a
large number of studies that have tried to understand the causal basis of parasite–mediated …

Establishment of patient-derived non–small cell lung cancer xenografts as models for the identification of predictive biomarkers

I Fichtner, J Rolff, R Soong, J Hoffmann, S Hammer… - Clinical cancer …, 2008 - AACR
Purpose: It was the aim of our study to establish an extensive panel of non-small cell lung
cancer (NSCLC) xenograft models useful for the testing of novel compounds and for the …

Insect immunity: an evolutionary ecology perspective

MT Siva-Jothy, Y Moret, J Rolff - Advances in insect physiology, 2005 - Elsevier
We review recent advances in our understanding of the mechanisms of insect immune
defence, but do so in a framework defined by the ecological and evolutionary forces that shape …

Copulation corrupts immunity: a mechanism for a cost of mating in insects

J Rolff, MT Siva-Jothy - Proceedings of the National …, 2002 - National Acad Sciences
There are well documented costs of mating in insects but little evidence for underlying
mechanisms. Here, we provide experimental evidence for a hormone-based mechanism that …

Antimicrobial defense and persistent infection in insects

ER Haine, Y Moret, MT Siva-Jothy, J Rolff - Science, 2008 - science.org
During 400 million years of existence, insects have rarely succumbed to the evolution of
microbial resistance against their potent antimicrobial immune defenses. We found that …

On sexual dimorphism in immune function

…, P Lindenfors, ER Pursall, J Rolff - … Transactions of the …, 2009 - royalsocietypublishing.org
… (Williams 1966) and (ii) males maximize fitness via mating rate and females via longevity
(Bateman 1948), this would select for higher investment in immune function in females (Rolff

Combination effects of antimicrobial peptides

…, DY Baeder, RR Regoes, J Rolff - Antimicrobial agents and …, 2016 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are ancient and conserved across the tree of life. Their efficacy
over evolutionary time has been largely attributed to their mechanisms of killing. Yet, the …