Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cells

KS Dingwell, CR Brunetti, RL Hendricks… - Journal of …, 1994 - Am Soc Microbiol
Herpes simplex virus (HSV) glycoproteins E and I (gE and gI) can act as a receptor for the
Fc domain of immunoglobulin G (IgG). To examine the role of HSV IgG Fc receptor in viral …

The herpes simplex virus gE-gI complex facilitates cell-to-cell spread and binds to components of cell junctions

KS Dingwell, DC Johnson - Journal of virology, 1998 - Am Soc Microbiol
The herpes simplex virus (HSV) glycoprotein complex gE-gI mediates the spread of viruses
between adjacent cells, and this property is especially evident for cells that form extensive …

Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virus

KS Dingwell, LC Doering, DC Johnson - Journal of virology, 1995 - Am Soc Microbiol
Two herpes simplex virus (HSV) glycoproteins E and I (gE and gI) form a heterooligomer
which acts as an Fc receptor and also facilitates cell-to-cell spread of virus in epithelial tissues …

The multiple decisions made by growth cones of RGCs as they navigate from the retina to the tectum in Xenopus embryos

KS Dingwell, CE Holt, WA Harris - Journal of neurobiology, 2000 - Wiley Online Library
Retinal ganglion cells (RGCs) of Xenopus laevis send axons along a stereospecific pathway
from the retina to their target the optic tectum. Viewed from the point of the growth cone, this …

Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning

SL Nutt, KS Dingwell, CE Holt… - Genes & …, 2001 - genesdev.cshlp.org
Signal transduction through the FGF receptor is essential for the specification of the vertebrate
body plan. Blocking the FGF pathway in early Xenopus embryos inhibits mesoderm …

Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins

…, JA Nathan, R Antrobus, KS Dingwell… - Journal of Cell …, 2014 - rupress.org
The regulated turnover of endoplasmic reticulum (ER)–resident membrane proteins
requires their extraction from the membrane lipid bilayer and subsequent proteasome-mediated …

The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms

…, J Varghese, R Gourlay, DG Campbell, KS Dingwell… - Science …, 2018 - science.org
Members of the casein kinase 1 (CK1) family of serine-threonine protein kinases are implicated
in the regulation of many cellular processes, including the cell cycle, circadian rhythms, …

Role of mannose-6-phosphate receptors in herpes simplex virus entry into cells and cell-to-cell transmission

…, RL Burke, B Hoflack, T Ludwig, KS Dingwell… - Journal of …, 1995 - Am Soc Microbiol
Herpes simplex virus (HSV) glycoprotein D (gD) is essential for virus entry into cells, is modified
with mannose-6-phosphate (M-6-P), and binds to both the 275-kDa M-6-P receptor (MPR…

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling

L Herhaus, MA Al-Salihi, KS Dingwell… - Open …, 2014 - royalsocietypublishing.org
Protein kinase ALK3/BMPR1A mediates bone morphogenetic protein (BMP) signalling through
phosphorylation and activation of SMADs 1/5/8. SMAD6, a transcriptional target of BMP, …

Herpes simplex virus gD and virions accumulate in endosomes by mannose 6-phosphate-dependent and-independent mechanisms

CR Brunetti, KS Dingwell, C Wale, FL Graham… - Journal of …, 1998 - Am Soc Microbiol
Herpes simplex virus (HSV) glycoprotein D (gD) is modified with mannose 6-phosphate (M6P)
and binds to M6P receptors (MPRs). MPRs are involved in the well-characterized …