User profiles for K. Hokamp

Karsten Hokamp

Bioinformatics Research Officer, Smurfit Institute of Genetics, Trinity College Dublin
Verified email at tcd.ie
Cited by 38180

Receptor‐mediated recognition of mycobacterial pathogens

…, C Ní Cheallaigh, C O'Farrelly, K Hokamp… - Cellular …, 2013 - Wiley Online Library
Mycobacteria are a genus of bacteria that range from the non‐pathogenic M ycobacterium
smegmatis to M ycobacterium tuberculosis, the causative agent of tuberculosis in humans. …

A recent polyploidy superimposed on older large-scale duplications in the Arabidopsis genome

G Blanc, K Hokamp, KH Wolfe - Genome research, 2003 - genome.cshlp.org
The Arabidopsis genome contains numerous large duplicated chromosomal segments, but
the different approaches used in previous analyses led to different interpretations regarding …

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37

…, S Doria, R Falsafi, K Hokamp… - The Journal of …, 2006 - journals.aai.org
… Differentially expressed genes with similar temporal expression profiles were clustered
using the partitioning algorithm K-means procedure (as implemented in TIGR’s Multiple …

Extensive genomic duplication during early chordate evolution

A McLysaght, K Hokamp, KH Wolfe - Nature genetics, 2002 - nature.com
Opinions on the hypothesis 1 that ancient genome duplications contributed to the vertebrate
genome range from strong skepticism 2, 3, 4 to strong credence 5, 6, 7. Previous studies …

[PDF][PDF] An infection-relevant transcriptomic compendium for Salmonella enterica Serovar Typhimurium

…, R Canals, JE Grissom, T Conway, K Hokamp… - Cell host & …, 2013 - cell.com
… CK, K. Hokamp, and JCDH analyzed and interpreted the data. AC, SS, K. Händler, SKS,
DLH, RC, and TC contributed to data analysis and interpretation. …

The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium

…, SK Sivasankaran, K Hokamp… - Proceedings of the …, 2012 - National Acad Sciences
More than 50 y of research have provided great insight into the physiology, metabolism, and
molecular biology of Salmonella enterica serovar Typhimurium (S. Typhimurium), but …

The complex relationship of gene duplication and essentiality

T Makino, K Hokamp, A McLysaght - Trends in genetics, 2009 - cell.com
… (K A ) between a duplicated gene and its closest paralog. The y-axis indicates the P E in each
K … However, when we focused on genes with K A >0.2, because highly constrained genes …

The 2R hypothesis and the human genome sequence

K Hokamp, A McLysaght, KH Wolfe - … Duplications and the Origin of Novel …, 2003 - Springer
… They measured the amount of divergence at synonymous sites (K,) between homologous
gene pairs. From this they found that the homologues were in four age classes arranged …

InnateDB: facilitating systems‐level analyses of the mammalian innate immune response

…, B Mah, T Munzner, K Hokamp… - Molecular systems …, 2008 - embopress.org
Although considerable progress has been made in dissecting the signaling pathways involved
in the innate immune response, it is now apparent that this response can no longer be …

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1

…, C Xue, SS Geiger, K Hokamp… - Proceedings of the …, 2015 - National Acad Sciences
The response to an innate immune challenge is conditioned by the time of day, but the
molecular basis for this remains unclear. In myeloid cells, there is a temporal regulation to …