We provide here a list of 221 P450 genes and 12 putative pseudogenes that have been
characterized as of December 14, 1992. These genes have been described in 31 eukaryotes (…

… Okuda H, Takayasu K. Budd-Chiari syndrome and hepatocel… Okuda K. What is the
precancerous lesion for hepatocellular … T, Suenaga M, Okuda K. Emergence of malignant lesions …

Viral vectors are promising tools for gene therapy and vaccines. Viral vector-based vaccines
can enhance immunogenicity without an adjuvant and induce a robust cytotoxic T …

The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …

… Using 3D confocal microscopy, we demonstrated the virus inside of these cells, (k) most
of which were ACE2 + (two independent replications). l, These epithelial cells were found to …

A total of 850 patients with hepatocellular carcinoma seen during the last 8 years were
analyzed retrospectively for survival in relation to treatment and disease stage. A new staging …

The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral …

… (J and K) Blinded histopathological evaluation of lung damage using DAD scoring (J) and
ATS ALI scoring (K) systems on days 2, 4, and 7 after mock or SARSCoV-2 MA10 infection. …

Autophagy is an essential process for physiological homeostasis, but its role in viral infection
is only beginning to be elucidated. We show here that the Atg5–Atg12 conjugate, a key …

Most patients infected with hepatitis C virus (HCV) develop chronic hepatitis. Unfortunately,
the pathological evolution of this disease over time is not completely understood. We studied …