User profiles for K. Theys
 | Kristof TheysKU Leuven Verified email at kuleuven.be Cited by 2074 |
Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research
… An additional online search on NCBI’s GenBank confirmed that they also have no
matches in any other sequences that are not assigned to SARS-CoV-2. A list of SARS-CoV-2-specific …
matches in any other sequences that are not assigned to SARS-CoV-2. A list of SARS-CoV-2-specific …
[HTML][HTML] Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study
Background Antiretroviral therapy (ART) is crucial for controlling HIV-1 infection through
wide-scale treatment as prevention and pre-exposure prophylaxis (PrEP). Potent tenofovir …
wide-scale treatment as prevention and pre-exposure prophylaxis (PrEP). Potent tenofovir …
HIV-1 genotypic drug resistance testing: digging deep, reaching wide?
K Van Laethem, K Theys, AM Vandamme - Current opinion in virology, 2015 - Elsevier
… These errors were especially detrimental for HIV-1 drug resistance testing as they mainly
occur in homo-polymer stretches which are commonly found within or adjacent to HIV-1 codons …
occur in homo-polymer stretches which are commonly found within or adjacent to HIV-1 codons …
[HTML][HTML] The impact of HIV-1 within-host evolution on transmission dynamics
… Kristof Theys is funded by a postdoctoral grant of the Fonds Wetenschappelijk Onderzoek
– Vlaanderen (FWO). Pieter Libin is funded by a doctoral grant of the Research Foundation – …
– Vlaanderen (FWO). Pieter Libin is funded by a doctoral grant of the Research Foundation – …
[HTML][HTML] HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics
… Even though some of these differences are statistically significant, they are limited to the
extent that they have no substantial impact on the remaining analyses, and are thus not further …
extent that they have no substantial impact on the remaining analyses, and are thus not further …
[HTML][HTML] An integrated map of HIV genome-wide variation from a population perspective
… Globally, over 90% of HIV infections belong to HIV-1 group M viruses, which have been
classified into 9 subtypes (AD, FH, J, K) and more than 50 circulating recombinant forms (CRFs) […
classified into 9 subtypes (AD, FH, J, K) and more than 50 circulating recombinant forms (CRFs) […
[HTML][HTML] A computational method for the identification of Dengue, Zika and Chikungunya virus species and genotypes
In recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika
viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is …
viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is …
[HTML][HTML] CRF19_cpx is an evolutionary fit HIV-1 variant strongly associated with rapid progression to AIDS in Cuba
… , CRF23_BG and CRF24_BG study sequences clustered mainly outside the cluster of the
respective CRF reference sequences precluding a reliable CRF assignment, but together they …
respective CRF reference sequences precluding a reliable CRF assignment, but together they …
VIRULIGN: fast codon-correct alignment and annotation of viral genomes
… Kristof Theys Kristof Theys … We thank the three anonymous reviewers for their
comments, as they have helped us to improve the software and manuscript. …
comments, as they have helped us to improve the software and manuscript. …
[HTML][HTML] Genetic diversity and selective pressure in hepatitis C virus genotypes 1–6: significance for direct-acting antiviral treatment and drug resistance
Treatment with pan-genotypic direct-acting antivirals, targeting different viral proteins, is the
best option for clearing hepatitis C virus (HCV) infection in chronically infected patients. …
best option for clearing hepatitis C virus (HCV) infection in chronically infected patients. …