Background Intrinsically unstructured proteins (IUPs) lack a well-defined three-dimensional
structure. Some of them may assume a locally stable structure under specific conditions, eg …

Background Accurate estimation of the isoelectric point (pI) based on the amino acid
sequence is useful for many analytical biochemistry and proteomics techniques such as 2-D …

Proteome-pI is an online database containing information about predicted isoelectric points
for 5029 proteomes calculated using 18 methods. The isoelectric point, the pH at which a …

The isoelectric point is the pH at which a particular molecule is electrically neutral due to the
equilibrium of positive and negative charges. In proteins and peptides, this depends on the …

We present a continuous benchmarking approach for the assessment of RNA secondary
structure prediction methods implemented in the CompaRNA web server. As of 3 October 2012, …

Proteome-pI 2.0 is an update of an online database containing predicted isoelectric points
and pK a dissociation constants of proteins and peptides. The isoelectric point—the pH at …

The Virus-X—Viral Metagenomics for Innovation Value—project was a scientific expedition
to explore and exploit uncharted territory of genetic diversity in extreme natural environments …

Phage vB_Tsc2631 infects the extremophilic bacterium Thermus scotoductus MAT2631 and
uses the Ts2631 endolysin for the release of its progeny. The Ts2631 endolysin is the first …

Protein–RNA interactions play fundamental roles in many biological processes, such as
regulation of gene expression, RNA splicing, and protein synthesis. The understanding of these …

Motivation: To date, only a few distinct successful approaches have been introduced to
reconstruct a protein 3D structure from a map of contacts between its amino acid residues (a 2D …