Large-scale perturbation databases, such as Connectivity Map (CMap) or Library of
Integrated Network-based Cellular Signatures (LINCS), provide enormous opportunities for …

Extracellular matrix (ECM) homeostasis is essential for normal tissue function, and its
disruption by iatrogenic injury, trauma, or disease results in fibrosis. Skin ECM homeostasis is …

Purpose Distant metastasis (DM) is the main cause of death for patients with human
papillomavirus (HPV)–related oropharyngeal cancers (OPCs); yet, there are few reliable predictors …

… El-Hachem, DMA Gendoo, and LS Ghoraie are the co-first authors of this article. … Fei-Fei
Liu for supporting Laleh Soltan Ghoraie financially. We thank John Chen and Ali Nawed for their …

The interactions between drugs and their target proteins induce altered expression of genes
involved in complex intracellular networks. The properties of these functional network …

Background Fatigue and insomnia are common symptoms experienced by breast cancer
patients undergoing adjuvant radiation therapy (RT), yet the underlying mechanisms of these …

Drug sensitivity biomarkers are molecular features informative for drug response. Previous
studies have identified many candidate drug-sensitivity signatures at the transcript level …

Identification of primary targets associated with phenotypes can facilitate exploration of the
underlying molecular mechanisms of compounds and optimization of the structures of …

This paper describes the implementation of a mashup that integrates travel services. There
are various travel services focusing on flight, train, or bus. However, none of them can plan a …

Protein isoforms are structurally similar proteins produced by alternative splicing of a single
gene or genes from the same family. Isoforms of a protein can perform the same, similar, or …