Crohn's disease is a lifelong disease arising from an interaction between genetic and
environmental factors, but observed predominantly in developed countries of the world. The …

Cancers Complicating Inflammatory Bowel Disease | NEJM Skip to main content NEJM Group
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The pathophysiology of microscopic colitis is unknown, although it is thought to be because
of an abnormal immune reaction to luminal antigens in predisposed hosts. Specific antigens …

Background The intestinal microbiota is suspected to play a role in colitis and particularly in
inflammatory bowel disease (IBD) pathogenesis. The aim was to compare the fecal …

… After infection, cells were fixed with 3% glutaraldehyde in 0.2 mol/L cacodylate buffer at 4C
for 2 hours and postfixed in 1% OsO 4 in cacodylate buffer at 4C for 1 hour. After dehydration …

Complex interactions between the host and the gut microbiota govern intestinal homeostasis
but remain poorly understood. Here we reveal a relationship between gut microbiota and …

CROHN'S disease (CD) and ulcerative colitis are the major forms of chronic inflammatory
bowel diseases in the western world, and occur in young adults with an estimated prevalence …

Objective The bacterial intestinal microbiota plays major roles in human physiology and
IBDs. Although some data suggest a role of the fungal microbiota in IBD pathogenesis, the …

Background The Vienna classification of Crohn's disease (CD) distinguishes three patient
subgroups according to disease behavior: stricturing, penetrating, and inflammatory. Our aim …

Background Reports of an increased risk of lymphoproliferative disorders in patients receiving
thiopurines for inflammatory bowel disease are controversial. We assessed this risk in a …