User profiles for L. Choleva

Lukas Choleva

Department of Biology and Ecology, Faculty of Science, University of Ostrava
Verified email at osu.cz
Cited by 1399

[HTML][HTML] Human beta cell regenerative drug therapy for diabetes: past achievements and future challenges

P Wang, E Karakose, L Choleva, K Kumar… - Frontiers in …, 2021 - frontiersin.org
A quantitative deficiency of normally functioning insulin-producing pancreatic beta cells is a
major contributor to all common forms of diabetes. This is the underlying premise for …

Rise and persistence of animal polyploidy: evolutionary constraints and potential

L Choleva, K Janko - Cytogenetic and genome research, 2013 - karger.com
The past decade has witnessed a tremendous increase in interest in polyploidy, which may
partly be related to the development of new powerful genetic and genomic tools. These have …

Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: A double-blind randomized controlled trial

V Vuksan, AL Jenkins, C Brissette, L Choleva… - Nutrition, Metabolism …, 2017 - Elsevier
Background and Aim Preliminary findings indicate that consumption of Salba-chia (Salvia
hispanica L.), an ancient seed, improves management of type 2 diabetes and suppresses …

Comparison of flax (Linum usitatissimum) and Salba-chia (Salvia hispanica L.) seeds on postprandial glycemia and satiety in healthy individuals: a randomized …

V Vuksan, L Choleva, E Jovanovski… - European journal of …, 2017 - nature.com
Results: Both Salba-chia and flax reduced blood glucose area under the curve over 120 min
by 82.5±19.7 mmol/l (P< 0.001) and 60.0±19.7 mmol/l (P= 0.014), respectively, relative to a …

[HTML][HTML] Disrupting the DREAM complex enables proliferation of adult human pancreatic β cells

…, X Liu, O Wood, H Liu, L Choleva… - The Journal of …, 2022 - Am Soc Clin Investig
Resistance to regeneration of insulin-producing pancreatic β cells is a fundamental challenge
for type 1 and type 2 diabetes. Recently, small molecule inhibitors of the kinase DYRK1A …

Nuclear and mitochondrial phylogeography of the European fire‐bellied toads Bombina bombina and Bombina variegata supports their independent histories

…, W Babik, M Stuglik, G Gollmann, L Choleva… - Molecular …, 2011 - Wiley Online Library
Exact location and number of glacial refugia still remain unclear for many European cold‐blooded
terrestrial vertebrates. We performed a fine‐scaled multilocus phylogeographic …

Synthesis of clonality and polyploidy in vertebrate animals by hybridization between two sexual species

L Choleva, K Janko, K De Gelas, J Bohlen… - …, 2012 - academic.oup.com
Because most clonal vertebrates have hybrid genomic constitutions, tight linkages are
assumed among hybridization, clonality, and polyploidy. However, predictions about how these …

Genetic diversity and distribution patterns of diploid and polyploid hybrid water frog populations (Pelophylax esculentus complex) across Europe

…, S Röthlisberger, L Choleva… - Molecular …, 2015 - Wiley Online Library
… As indicated by our microsatellite data, this population also contains L genomes that are
obviously distinct from L genomes of other central European populations. Whether these …

Standard Metabolic Rate (SMR) is inversely related to erythrocyte and genome size in allopolyploid fish of the Cobitis taenia hybrid complex

S Maciak, K Janko, J Kotusz, L Choleva… - Functional …, 2011 - Wiley Online Library
… where a is the slope of the linear regression of dissolved oxygen concentration with time (ΔO
Sat per h), V is the volume of the metabolic chamber (L) and α is the coefficient of solubility …

Divergence with gene flow between Ponto‐Caspian refugia in an anadromous cyprinid Rutilus frisii revealed by multiple gene phylogeography

P Kotlik, S MarkovA, L Choleva… - Molecular …, 2008 - Wiley Online Library
… Lukáš Choleva used various molecular markers for fish phylogenetics and phylogeography
while being a PhD student at Libêchov. Nina G. Bogutskaya is studying zoogeography and …