[HTML][HTML] Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs

JES Nunes, MA Duque, TF de Freitas, L Galina… - Molecules, 2020 - mdpi.com
Roughly a third of the world’s population is estimated to have latent Mycobacterium tuberculosis
infection, being at risk of developing active tuberculosis (TB) during their lifetime. Given …

Left ventricular global longitudinal systolic strain predicts adverse remodeling and subsequent cardiac events in patients with acute myocardial infarction treated with …

…, MJ García-González, BM López, MA Duque… - The international journal …, 2015 - Springer
To determine whether left ventricular (LV) global longitudinal strain (GLS) predicts adverse
LV remodeling and cardiac events. In a prospective cohort study of patients with acute …

The variability of EEG functional connectivity of young ADHD subjects in different resting states

…, E Pereda, S Mañas, LD Méndez, MR Duque… - Clinical …, 2016 - Elsevier
Objective To assess ADHD from global measures of EEG functional connectivity and their
temporal variability in different resting states. Methods EEGs from sixteen cortical regions were …

[HTML][HTML] Hatching of parasitic nematode eggs: a crucial step determining infection

…, RK Grencis, M Berriman, MA Duque-Correa - Trends in …, 2022 - cell.com
Although hatching from eggs is fundamental for nematode biology it remains poorly understood.
For animal-parasitic nematodes in particular, advancement has been slow since the …

[HTML][HTML] Organoids–new models for host–helminth interactions

MA Duque-Correa, RM Maizels, RK Grencis… - Trends in …, 2020 - cell.com
Organoids are multicellular culture systems that replicate tissue architecture and function,
and are increasingly used as models of viral, bacterial, and protozoan infections. Organoids …

B7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals

N Mirza, MA Duque, AL Dominguez… - The Journal of …, 2010 - journals.aai.org
T cell responses are compromised in the elderly. The B7-CD28 family receptors are critical
in the regulation of immune responses. We evaluated whether the B7-family and CD28-family …

Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis

…, D Oberbeck‐Müller, MA Duque‐Correa… - European journal of …, 2012 - Wiley Online Library
As a hallmark of tuberculosis (TB), Mycobacterium tuberculosis (MTB) induces granulomatous
lung lesions and systemic inflammatory responses during active disease. Molecular …

Nitrous Oxide Abuse and Vitamin B12 Action in a 20-Year-Old Woman: A Case Report

MA Duque, JL Kresak, A Falchook… - Laboratory …, 2015 - academic.oup.com
Herein, we report a case of a 20-year-old (ethnicity not reported) woman with a history of
nitrous oxide abuse and clinical symptoms consistent with spinal cord subacute combined …

Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas

MA Duque-Correa, AA Kühl… - Proceedings of the …, 2014 - National Acad Sciences
Lung granulomas develop upon Mycobacterium tuberculosis (Mtb) infection as a hallmark
of human tuberculosis (TB). They are structured aggregates consisting mainly of Mtb-infected …

Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth

S Zorro Manrique, MA Duque Correa… - Journal of Experimental …, 2011 - rupress.org
Regulatory T cells (T reg cells) are characterized by the expression of the forkhead lineage-specific
transcription factor Foxp3, and their main function is to suppress T cells. While …