The ability of cells to adhere to each other and to their surrounding extracellular matrices is
essential for a multicellular existence. Adhesion provides physical support for cells, regulates …

Syndecan-4 is a ubiquitous transmembrane proteoglycan that localizes to the focal adhesions
of adherent cells and binds to a range of extracellular ligands, including growth factors …

The formation, maturation, and dissolution of focal adhesions are basic prerequisites of cell
migration and rely on the recruitment, signalling, and endocytosis of integrins. In many …

The binding of integrin adhesion receptors to their extracellular matrix ligands controls cell
morphology, movement, survival, and differentiation in various developmental, homeostatic, …

Cell migration in wound healing and disease is critically dependent on integration with the
extracellular matrix, but the receptors that couple matrix topography to migratory behavior …

… MD Bass was supported by grant number 088419. We thank the Medical Research Council
and Wolfson Foundation for supporting the Wolfson Bioimaging Facility at the University of …

Cell migration during wound healing requires adhesion receptor turnover to enable the
formation and disassembly of cell-extracellular matrix contacts. Although recent advances have …

Precise spatiotemporal coordination of integrin adhesion complex dynamics is essential for
efficient cell migration. For cells adherent to fibronectin, differential engagement of α 5 β 1 …

The fibronectin receptors α 5 β 1 integrin and syndecan-4 cocluster in focal adhesions and
coordinate cell migration by making individual contributions to the suppression of RhoA …

The syndecan family of transmembrane proteoglycans cooperate with integrins to regulate
both early and late events in adhesion formation. The heparan sulphate chains substituted on …