User profiles for M. D. Humphries
Mark D HumphriesProfessor of Computational Neuroscience, University of Nottingham Verified email at nottingham.ac.uk Cited by 5569 |
The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward.
MD Humphries, TJ Prescott - Progress in neurobiology, 2010 - Elsevier
… The mediodorsal thalamus (MD) is the main thalamic target of the VP subdivisions in the
shell-based circuit; they also project to lateral hypothalamus (LH) and PPn. (c) The core retains …
shell-based circuit; they also project to lateral hypothalamus (LH) and PPn. (c) The core retains …
Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit
MD Humphries, R Wood, K Gurney - Neural networks, 2009 - Elsevier
The striatum, the principal input structure of the basal ganglia, is crucial to both motor
control and learning. It receives convergent input from all over the neocortex, hippocampal …
control and learning. It receives convergent input from all over the neocortex, hippocampal …
Effectiveness of revascularisation for the ulcerated foot in patients with diabetes and peripheral artery disease: a systematic review
Introduction Peripheral artery disease (PAD) is associated with an increased likelihood of
delayed or non‐healing of a diabetes‐related foot ulcer, gangrene, and amputation. The …
delayed or non‐healing of a diabetes‐related foot ulcer, gangrene, and amputation. The …
[HTML][HTML] Network 'small-world-ness': a quantitative method for determining canonical network equivalence
MD Humphries, K Gurney - PloS one, 2008 - journals.plos.org
Background Many technological, biological, social, and information networks fall into the
broad class of ‘small-world’ networks: they have tightly interconnected clusters of nodes, and a …
broad class of ‘small-world’ networks: they have tightly interconnected clusters of nodes, and a …
The DNA sequence and analysis of human chromosome 6
…, GR Howell, E Huckle, SJ Humphray, MD Humphries… - Nature, 2003 - nature.com
Chromosome 6 is a metacentric chromosome that constitutes about 6% of the human
genome. The finished sequence comprises 166,880,988 base pairs, representing the largest …
genome. The finished sequence comprises 166,880,988 base pairs, representing the largest …
The brainstem reticular formation is a small-world, not scale-free, network
MD Humphries, K Gurney… - Proceedings of the …, 2006 - royalsocietypublishing.org
Recently, it has been demonstrated that several complex systems may have simple graph-theoretic
characterizations as so-called ‘small-world’ and ‘scale-free’ networks. These …
characterizations as so-called ‘small-world’ and ‘scale-free’ networks. These …
A physiologically plausible model of action selection and oscillatory activity in the basal ganglia
MD Humphries, RD Stewart… - Journal of Neuroscience, 2006 - Soc Neuroscience
The basal ganglia (BG) have long been implicated in both motor function and dysfunction. It
has been proposed that the BG form a centralized action selection circuit, resolving conflict …
has been proposed that the BG form a centralized action selection circuit, resolving conflict …
A robot model of the basal ganglia: behavior and intrinsic processing
… Humphries and Gurney extended the original model of intrinsic basal ganglia processing
to include basal ganglia-thalamocortical loops (Humphries & Gurney, 2002). This work led to …
to include basal ganglia-thalamocortical loops (Humphries & Gurney, 2002). This work led to …
[HTML][HTML] Dopaminergic control of the exploration-exploitation trade-off via the basal ganglia
We continuously face the dilemma of choosing between actions that gather new information
or actions that exploit existing knowledge. This “exploration-exploitation” trade-off depends …
or actions that exploit existing knowledge. This “exploration-exploitation” trade-off depends …
[HTML][HTML] The contemporary management of renal artery aneurysms
…, C Lee, NS Cayne, J Loeffler, MD Humphries… - Journal of vascular …, 2015 - Elsevier
Background Renal artery aneurysms (RAAs) are rare, with little known about their natural
history and growth rate or their optimal management. The specific objectives of this study were …
history and growth rate or their optimal management. The specific objectives of this study were …