… Whether in vitro kinetics are relevant in vivo is currently unknown, nor do we know the basis
for the decline in invasion capacity after egress observed in vitro (Boyle, Wilson and Beeson …

The RTS,S vaccine has recently been recommended for implementation as a childhood
vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of …

Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …

Objective: The authors sought to investigate the detection of non‐eosinophilic asthma using
induced sputum. Although this is an important subtype of clinical asthma, its recognition is …

Rationale: Patients with refractory asthma have persistent symptoms despite maximal treatment
with inhaled corticosteroids and long-acting bronchodilators. The availability of add-on …

The human brain has undergone substantial change since humans diverged from chimpanzees
and the other great apes 1 , 2 . However, the genetic and developmental programs that …

BACKGROUND:: Allergic bronchopulmonary aspergillosis (ABPA) complicates chronic asthma
and results from hypersensitivity to the fungus Aspergillus fumigatus, causing an intense …

The community structure of Jamaican coral reefs has undergone drastic change since mass
mortalities of the long-spined black sea urchin Diadema antillarum Philippi occurred in 1983…

Background: The role of the innate immune system in the pathogenesis of asthma is unclear.
Activation of innate immune receptors in response to bacterial lipopolysaccharide, viral …

Erythrocyte invasion by the merozoite is an obligatory stage in Plasmodium parasite infection
and essential to malaria disease progression. Attempts to study this process have been …