User profiles for M. P. Zwart
Mark P. ZwartSenior Researcher, Netherlands Institute of Ecology (NIOO-KNAW) Verified email at nioo.knaw.nl Cited by 2030 |
The evolutionary genetics of emerging plant RNA viruses
Over the years, agriculture across the world has been compromised by a succession of
devastating epidemics caused by new viruses that spilled over from reservoir species or by new …
devastating epidemics caused by new viruses that spilled over from reservoir species or by new …
Matters of size: genetic bottlenecks in virus infection and their potential impact on evolution
For virus infections of multicellular hosts, narrow genetic bottlenecks during transmission and
within-host spread appear to be widespread. These bottlenecks will affect the maintenance …
within-host spread appear to be widespread. These bottlenecks will affect the maintenance …
[HTML][HTML] Metagenomic studies of viruses in weeds and wild plants: a powerful approach to characterise variable virus communities
High throughput sequencing (HTS) has revolutionised virus detection and discovery, allowing
for the untargeted characterisation of whole viromes. Viral metagenomics studies have …
for the untargeted characterisation of whole viromes. Viral metagenomics studies have …
An experimental test of the independent action hypothesis in virus–insect pathosystems
The ‘independent action hypothesis’ (IAH) states that each pathogen individual has a non-zero
probability of causing host death and that pathogen individuals act independently. IAH …
probability of causing host death and that pathogen individuals act independently. IAH …
[HTML][HTML] Effect of donor-recipient relatedness on the plasmid conjugation frequency: a meta-analysis
JB Alderliesten, SJN Duxbury, MP Zwart… - BMC microbiology, 2020 - Springer
Background Conjugation plays a major role in the transmission of plasmids encoding
antibiotic resistance genes in both clinical and general settings. The conjugation efficiency is …
antibiotic resistance genes in both clinical and general settings. The conjugation efficiency is …
[HTML][HTML] One Is Enough: In Vivo Effective Population Size Is Dose-Dependent for a Plant RNA Virus
Effective population size (N e ) determines the strength of genetic drift and the frequency of
co-infection by multiple genotypes, making it a key factor in viral evolution. Experimental …
co-infection by multiple genotypes, making it a key factor in viral evolution. Experimental …
A viral protein mediates superinfection exclusion at the whole-organism level but is not required for exclusion at the cellular level
Superinfection exclusion (SIE), the ability of an established virus infection to interfere with a
secondary infection by the same or a closely related virus, has been described for different …
secondary infection by the same or a closely related virus, has been described for different …
[HTML][HTML] Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase
While synonymous mutations were long thought to be without phenotypic consequences,
there is growing evidence they can affect gene expression, protein folding, and ultimately the …
there is growing evidence they can affect gene expression, protein folding, and ultimately the …
[HTML][HTML] Within-host spatiotemporal dynamics of plant virus infection at the cellular level
A multicellular organism is not a monolayer of cells in a flask; it is a complex, spatially structured
environment, offering both challenges and opportunities for viruses to thrive. Whereas …
environment, offering both challenges and opportunities for viruses to thrive. Whereas …
Population size mediates the contribution of high-rate and large-benefit mutations to parallel evolution
Mutations with large fitness benefits and mutations occurring at high rates may both cause
parallel evolution, but their contribution is predicted to depend on population size. Moreover, …
parallel evolution, but their contribution is predicted to depend on population size. Moreover, …