User profiles for M. V. Tirrell

Matthew Tirrell

Director, Institute for Molecular Engineering, University of Chicago
Verified email at uchicago.edu
Cited by 35941

Molecular engineering solutions for therapeutic peptide delivery

…, JM Ting, S Srivastava, JL LaBelle, MV Tirrell - Chemical Society …, 2017 - pubs.rsc.org
… Samanvaya Srivastava is a postdoctoral researcher at The University of Chicago in Matthew
Tirrell's laboratory. His research interests are in the areas of polyelectrolyte complexation …

Polyelectrolyte complexation

S Srivastava, MV Tirrell - Advances in chemical physics, 2016 - Wiley Online Library
This chapter reviews the theoretical and experimental description of complexes and
complex‐based hybrid self‐assemblies composed of flexible polyelectrolytes, with a special …

Polyampholyte physics: Liquid–liquid phase separation and biological condensates

J Dinic, AB Marciel, MV Tirrell - Current opinion in colloid & interface …, 2021 - Elsevier
Here we review the current understanding of molecular interactions that govern liquid–liquid
phase separation (LLPS) of biological condensates. The connection between sequence, …

Phase behavior and salt partitioning in polyelectrolyte complex coacervates

…, M Andreev, AB Marciel, JJ De Pablo, MV Tirrell - …, 2018 - ACS Publications
Polyelectrolyte complexes are omnipresent both in nature and in the technological world,
including nucleotide condensates, biological marine adhesives, food stabilizers, encapsulants, …

Adhesion and surface interactions of a self‐healing polymer with multiple hydrogen‐bonding groups

…, KE Feldman, J Yu, MV Tirrell… - Advanced Functional …, 2014 - Wiley Online Library
The surface properties and self‐adhesion mechanism of self‐healing poly(butyl acrylate) (PBA)
copolymers containing comonomers with 2‐ureido‐4[1H]‐pyrimidinone quadruple …

A versatile approach to high-throughput microarrays using thiol-ene chemistry

…, MD Dimitriou, ST Hikita, ND Treat, MV Tirrell… - Nature …, 2010 - nature.com
Microarray technology has become extremely useful in expediting the investigation of large
libraries of materials in a variety of biomedical applications, such as in DNA chips, protein …

A study of polyelectrolyte brushes formed from adsorption of amphiphilic diblock copolymers using the surface forces apparatus

…, F Li, P Schorr, J Yang, JW Mays, MV Tirrell - …, 2002 - ACS Publications
Polyelectrolyte brushes were formed at the interface between hydrophobized mica and water
by adsorbing amphiphilic diblock copolymers consisting of a hydrophobic and a charged …

Oligonucleotide–peptide complexes: phase control by hybridization

…, L Leon, AJ Bologna, JR Rivera, MV Tirrell - Journal of the …, 2018 - ACS Publications
When oppositely charged polymers are mixed, counterion release drives phase separation;
understanding this process is a key unsolved problem in polymer science and biophysical …

Structure and rheology of polyelectrolyte complex coacervates

AB Marciel, S Srivastava, MV Tirrell - Soft Matter, 2018 - pubs.rsc.org
Scattering investigations of the structure and chain conformations, and the rheological properties
of polyelectrolyte complexes (PECs) comprising model polyelectrolytes are presented. …

[HTML][HTML] Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma

…, B Auffinger, DA Wainwright, MS Lesniak, MV Tirrell - Biomaterials, 2014 - Elsevier
… and Cy7-CREKA-micelles were spherical in shape and the addition of the pentapeptide
increased the average particle size and zeta potential from 7.6 to 8.2 nm, and −27.4 to −12.6 mV