Homeotic genes are master control genes that specify the body plan and regulate development
of higher organisms. They share a common sequence element of 180 bp, the homeobox, …

… Binding studies indicated that the Antp(C39S) polypeptide interacts as a monomer with its
BS2 target DNA (Affolter et al., 1990), which is in agreement with the … Equilibrium DNA …

The Hox genes are clustered sets of homeobox-containing genes that play a central role in
animal development. Recent genetic and molecular data suggest that Hox proteins interact …

Context. ESPRESSO is the new high-resolution spectrograph of ESO’s Very Large Telescope
(VLT). It was designed for ultra-high radial-velocity (RV) precision and extreme spectral …

… We crystallized Noggin–BMP-7 at 10 mg ml -1 from hanging drops in 0.6 M disodium, 1.0
M monopotassium phosphate (∼pH 6.5). Large single crystals grew overnight at ambient …

… This is in accordance with the halflife of the complex as measured by gel mobility shift (Affolter
et al., 1990a). At titration ratios > 1.0 a precipitate formed, which could be redissolved by …

The use of genetic mutations to study protein functions in vivo is a central paradigm of modern
biology. Recent advances in reverse genetics such as RNA interference and morpholinos …

Dysregulation of the initial, innate immune response to bacterial infection may lead to septic
shock and death. Toll-like receptors (TLRs) play a crucial role in this innate immune …

… Proteomic developments, applications and potential in the field of nutrition have been
specifically addressed in another review issued by our group [Kussmann, M., Affolter, M., Fay, LB, …

Morphogens have been linked to numerous developmental processes, including organ
patterning and the control of organ size. Here we review how different experimental approaches …