G-protein-coupled receptors (GPCRs) are physiologically important membrane proteins that
sense signalling molecules such as hormones and neurotransmitters, and are the targets of …

Over the past decade, we have observed a massive increase in the amount of information
describing protein sequences from a variety of organisms. 1, 2 While this may reflect the …

The regulatory interactions between transcription factors and their target genes can be
conceptualised as a directed graph. At a global level, these regulatory networks display a scale-…

This study describes comprehensive polling of transcription start and termination sites and
analysis of previously unidentified full-length complementary DNAs derived from the mouse …

… (D) mRNA noise ( σ m 2 / μ m 2 ) scales inversely with mRNA mean number (μ m ) and is …
The mRNA Fano factors ( σ m 2 / μ m ) of the measured strains have similar values centered …

Cellular processes often depend on stable physical associations between proteins. Despite
recent progress, knowledge of the composition of human protein complexes remains limited. …

The helix-turn-helix (HTH) domain is a common denominator in basal and specific transcription
factors from the three super-kingdoms of life. At its core, the domain comprises of an …

Irrigated rice (Oryza sativa L.) yield increases in Asia have slowed down in recent years.
Further, yield increases are likely to occur in smaller increments through fine-tuning of crop …

Intrinsically disordered proteins (IDPs) are enriched in signaling and regulatory functions
because disordered segments permit interaction with several proteins and hence the re-use of …

… It is a medium-sized tree, normally up to 25 m tall, occasionally reaching up to 35 m and
with diameter up to 150 cm. The bole is without buttresses; it is usually twisted or leaning …