Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic mapping of the interactions between drugs and bacteria has only started …

Aberrant cell signaling can cause cancer and other diseases and is a focal point of drug
research. A common approach is to infer signaling activity of pathways from gene expression. …

Bacterial metabolism plays a fundamental role in gut microbiota ecology and host–microbiome
interactions. Yet the metabolic capabilities of most gut bacteria have remained unknown. …

Extracting signalling pathway activities from transcriptome data is important to infer mechanistic
origins of transcriptomic dysregulation, for example in disease. A popular method to do …

The gut microbiota is increasingly being recognized as a key site of metabolism for drugs and
other xenobiotic compounds that are relevant to human health. The molecular complexity …

An optimal supply of L-methionine (L-Met) improves muscle growth, whereas over-supplementation
exerts adverse effects. To understand the underlying mechanisms, this study aims at …

The replacement of fishmeal by plant proteins in aquafeeds imposes the use of synthetic
methionine (MET) sources to balance the amino acid composition of alternative diets and so to …

Methionine (Met) supplementation is common practice in broilers to support nutrition, yet
there are gaps in the understanding of its role in systemic physiology. Furthermore, several …

Methionine (Met) as an essential amino acid has key importance in a variety of metabolic
pathways. This study investigated the influence of three dietary Met supplements (0.21% L-Met, …

The objective of this study was to investigate the effects of dietary supplementation of Bacillus
(B.) amyloliquefaciens on growth performance, diarrhea, systemic immunity, and intestinal …