MicroRNAs (miRNAs) are endogenous small RNAs that can regulate target mRNAs by
binding to their 3′‐UTRs. A single miRNA can regulate many mRNA targets, and several …

Genes normally resident in euchromatic domains are silenced when packaged into
heterochromatin, as exemplified in Drosophila melanogaster by position effect variegation (PEV). …

… greater amounts of mRNA to the total transgenes under silencing conditions (Pal Bhadra et
… performed as described (Pal Bhadra et enhancement of the translation of the oskar mRNA …

In recent years, long non-coding RNAs (lncRNAs) have attracted the attention of researchers
with their involvement in all facets of life. LncRNAs are transcripts of more than 200 …

Drosophila Polycomb group (PcG) proteins silence homeotic genes through binding to
Polycomb group response elements (PREs). Fab-7 is a PRE-containing regulatory element from …

MicroRNAs (miRNAs) are a class of small, non-coding RNAs that are involved in the regulation
of gene expression at the post-transcriptional level. MicroRNAs play an important role in …

When two to six copies of a white promoter-Alcohol dehydrogenase (Adh) reporter fusion
gene are introduced into the genome, the expression is progressively reduced both in larvae …

A series of benzothiazole and benzoxazole linked pyrrolobenzodiazepine conjugates attached
through different alkane or alkylamide spacers was prepared. Their anticancer activity, …

A new series of imidazo[2,1-b]pyridine/pyrimidine chalcone derivatives were synthesized
and evaluated for their anticancer activity. These chalcone derivatives showed promising …

Aiming to develop multitarget drugs for the anticancer treatment, a new class of chalcone-pyrrolo[2,1-c]
[1,4]benzodiazepine (PBD) conjugates linked through a 1,2,3-triazole moiety …