User profiles for N. C. Knox
Natalie C KnoxPublic Health Agency of Canada Verified email at canada.ca Cited by 2172 |
[HTML][HTML] Metagenomics: the next culture-independent game changer
A trend towards the abandonment of obtaining pure culture isolates in frontline laboratories
is at a crossroads with the ability of public health agencies to perform their basic mandate of …
is at a crossroads with the ability of public health agencies to perform their basic mandate of …
The gut microbiome as a target for IBD treatment: are we there yet?
Purpose of review This review aims to highlight recent research on the gut microbiome in IBD
and the application of microbiome-modulating therapies for the treatment of IBD including …
and the application of microbiome-modulating therapies for the treatment of IBD including …
[HTML][HTML] A fungal world: could the gut mycobiome be involved in neurological disease?
The human microbiome has received decades of attention from scientific and medical
research communities. The human gastrointestinal tract is host to immense populations of …
research communities. The human gastrointestinal tract is host to immense populations of …
[HTML][HTML] A comparative study of the gut microbiota in immune-mediated inflammatory diseases—does a common dysbiosis exist?
Background Immune-mediated inflammatory disease (IMID) represents a substantial health
concern. It is widely recognized that IMID patients are at a higher risk for developing …
concern. It is widely recognized that IMID patients are at a higher risk for developing …
SNVPhyl: a single nucleotide variant phylogenomics pipeline for microbial genomic epidemiology
The recent widespread application of whole-genome sequencing (WGS) for microbial
disease investigations has spurred the development of new bioinformatics tools, including a …
disease investigations has spurred the development of new bioinformatics tools, including a …
[HTML][HTML] A comparison of whole genome sequencing of SARS-CoV-2 using amplicon-based sequencing, random hexamers, and bait capture
Genome sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
increasingly important to monitor the transmission and adaptive evolution of the virus. The …
increasingly important to monitor the transmission and adaptive evolution of the virus. The …
The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes
Objective To examine the gut microbiota in individuals with and without pediatric‐onset
multiple sclerosis (MS). Methods We compared stool‐derived microbiota of Canadian Pediatric …
multiple sclerosis (MS). Methods We compared stool‐derived microbiota of Canadian Pediatric …
The gut microbiome in inflammatory bowel disease: lessons learned from other immune-mediated inflammatory diseases
There is a growing appreciation for the role of the gut microbiome in human health and disease.
Aided by advances in sequencing technologies and analytical methods, recent research …
Aided by advances in sequencing technologies and analytical methods, recent research …
[HTML][HTML] Highlighting clinical metagenomics for enhanced diagnostic decision-making: a step towards wider implementation
Clinical metagenomics (CMg) is the discipline that refers to the sequencing of all nucleic
acid material present within a clinical specimen with the intent to recover clinically relevant …
acid material present within a clinical specimen with the intent to recover clinically relevant …
[HTML][HTML] Comparison of Sample Preparation Methods Used for the Next-Generation Sequencing of Mycobacterium tuberculosis
The advent and widespread application of next-generation sequencing (NGS) technologies
to the study of microbial genomes has led to a substantial increase in the number of studies …
to the study of microbial genomes has led to a substantial increase in the number of studies …