User profiles for N. P. Mongan

Nigel Mongan

University of Nottingham
Verified email at nottingham.ac.uk
Cited by 7764

Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with …

…, JL Persson, LJ Gudas, NP Mongan - Stem cells and …, 2009 - liebertpub.com
… 3 Mongan NPLJGudas 2007Diverse actions of retinoid receptors in cancer prevention and
treatmentDifferentiation75853870. 3. Mongan NP and LJ Gudas. (2007). Diverse actions of …

[HTML][HTML] Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics

…, S de Brot, L Grau-Roma, NP Mongan… - Acta Veterinaria …, 2017 - Springer
Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are
27 times higher than in people. Prognosis in both species is relatively poor, with 5 year OSA …

Androgen insensitivity syndrome

NP Mongan, R Tadokoro-Cuccaro, T Bunch… - Best practice & research …, 2015 - Elsevier
Androgen insensitivity syndrome (AIS) results from androgen receptor dysfunction and is a
common cause of disorder of sex development. The AIS phenotype largely depends on the …

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

IU Haussmann, Z Bodi, E Sanchez-Moran, NP Mongan… - Nature, 2016 - nature.com
N 6 -methyladenosine (m 6 A) is the most common internal modification of eukaryotic
messenger RNA (mRNA) and is decoded by YTH domain proteins 1 , 2 , 3 , 4 , 5 , 6 , 7 . The …

Identification of factors required for m6A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI

…, H Li, S Zhong, G De Jaeger, NP Mongan… - New …, 2017 - Wiley Online Library
N6‐adenosine methylation (m 6 A) of mRNA is an essential process in most eukaryotes, but
its role and the status of factors accompanying this modification are still poorly understood. …

Role of androgen receptor and associated lysine‐demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer

…, DS Scherr, LJ Gudas, NP Mongan - Molecular …, 2011 - Wiley Online Library
Bladder cancer is approximately three times more common in men as compared to women.
We and others have previously investigated the contribution of androgens and the androgen …

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants

…, L Fong, K Mika, S Chigurupati, L Yon, NP Mongan… - elife, 2016 - elifesciences.org
10.7554/eLife.11994.001 A major constraint on the evolution of large body sizes in animals
is an increased risk of developing cancer. There is no correlation, however, between body …

Increased Expression of the Polycomb Group Gene, EZH2, in Transitional Cell Carcinoma of the Bladder

JD Raman, NP Mongan, SK Tickoo, SA Boorjian… - Clinical cancer …, 2005 - AACR
… Grant support: NIH grants R01DE10389 and R01CA097543 (LJ Gudas) and AACR Cancer
Research Foundation of America postdoctoral fellowship in cancer prevention (NP Mongan). …

Diverse actions of retinoid receptors in cancer prevention and treatment

NP Mongan, LJ Gudas - Differentiation, 2007 - Elsevier
Retinoids (retinol [vitamin A] and its biologically active metabolites) are essential signaling
molecules that control various developmental pathways and influence the proliferation and …

Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer

S Boorjian, S Ugras, NP Mongan, LJ Gudas, X You… - Urology, 2004 - Elsevier
OBJECTIVES: To evaluate the expression of the androgen receptor (AR) in transitional cell
carcinoma (TCC) of the bladder, and to assess whether its expression correlated with …