The Ca 2+ -binding protein calmodulin (CaM) is a well-known regulator of ion-channel activity.
Consequently, the Protein Data Bank contains many structures of CaM in complex with …

The epithelial Ca 2+ channel transient receptor potential vanilloid 5 (TRPV5) constitutes the
apical entry gate for active Ca 2+ reabsorption in the kidney. Ca 2+ influx through TRPV5 …

Our international study, ‘Your DNA, Your Say’, uses film and an online cross-sectional survey
to gather public attitudes toward the donation, access and sharing of DNA information. We …

It is generally acknowledged that, for reproducibility and progress of human genomic
research, data sharing is critical. For every sharing transaction, a successful data exchange is …

The epithelial Ca 2+ channels TRPV5/6 (transient receptor potential vanilloid 5/6) are thoroughly
regulated in order to fine-tune the amount of Ca 2+ reabsorption. Calmodulin has been …

In order to examine the origins of the large positive cooperativity (ΔG 0 coop = −2.9 kcal mol
−1 ) of trimethoprim (TMP) binding to a bacterial dihydrofolate reductase (DHFR) in the …

DNAdigest's mission is to investigate and address the issues hindering efficient and ethical
genomic data sharing in the human genomics research community. We conducted …

The transient receptor potential vanilloid channel subfamily member 5 (TRPV5) is a highly
selective calcium ion channel predominately expressed in the kidney epithelium that plays an …

Urinary proteins that leak through the abnormal glomerulus in nephrotic syndrome may affect
tubular transport by interacting with membrane transporters on the luminal side of tubular …

Solution structure of human dihydrofolate reductase in its complex with trimethoprim and
NADPH Page 1 NMR structure note Solution structure of human dihydrofolate reductase in its …