User profiles for O. K. Smith
Owen SmithStanford University School of Medicine Verified email at stanford.edu Cited by 841 |
A general equation for relaxation oscillations
N Levinson, OK Smith - 1942 - projecteuclid.org
… SMITH … SMITH … This method has been used by one of the authors, OK Smith, in his
thesis at MI T. (May, 1941) toprove Theorem I in a more restrictive form and with g(x) …
thesis at MI T. (May, 1941) toprove Theorem I in a more restrictive form and with g(x) …
Chromatin structure and replication origins: determinants of chromosome replication and nuclear organization
OK Smith, MI Aladjem - Journal of Molecular Biology, 2014 - Elsevier
The DNA replication program is, in part, determined by the epigenetic landscape that governs
local chromosome architecture and directs chromosome duplication. Replication must …
local chromosome architecture and directs chromosome duplication. Replication must …
DiMeLo-seq: a long-read, single-molecule method for mapping protein–DNA interactions genome wide
Studies of genome regulation routinely use high-throughput DNA sequencing approaches
to determine where specific proteins interact with DNA, and they rely on DNA amplification …
to determine where specific proteins interact with DNA, and they rely on DNA amplification …
Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts
10.7554/eLife.27024.001 RNA is a critical component of chromatin in eukaryotes, both as a
product of transcription, and as an essential constituent of ribonucleoprotein complexes that …
product of transcription, and as an essential constituent of ribonucleoprotein complexes that …
Eigenvalues of a symmetric 3× 3 matrix
OK Smith - Communications of the ACM, 1961 - dl.acm.org
Recently, in order to find the principal moments of inertia of a large number of rigid bodies, it
was necessary to compute the eigenvalues of many real, symmetric 3 × 3 matrices. The …
was necessary to compute the eigenvalues of many real, symmetric 3 × 3 matrices. The …
[HTML][HTML] Distinct epigenetic features of differentiation-regulated replication origins
OK Smith, RG Kim, H Fu, MM Martin, CM Lin… - Epigenetics & …, 2016 - Springer
Background Eukaryotic genome duplication starts at discrete sequences (replication origins)
that coordinate cell cycle progression, ensure genomic stability and modulate gene …
that coordinate cell cycle progression, ensure genomic stability and modulate gene …
Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability
Chromatin structure affects DNA replication patterns, but the role of specific chromatin modifiers
in regulating the replication process is yet unclear. We report that phosphorylation of the …
in regulating the replication process is yet unclear. We report that phosphorylation of the …
[HTML][HTML] Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactions
Non-coding RNAs (ncRNAs) are transcribed throughout the genome and provide regulatory
inputs to gene expression through their interaction with chromatin. Yet, the genomic targets …
inputs to gene expression through their interaction with chromatin. Yet, the genomic targets …
[HTML][HTML] The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
…, K Utani, H Fu, CE Redon, AB Marks, OK Smith… - Nature …, 2018 - nature.com
Cell cycle progression in mammals is modulated by two ubiquitin ligase complexes, CRL4
and SCF, which facilitate degradation of chromatin substrates involved in the regulation of …
and SCF, which facilitate degradation of chromatin substrates involved in the regulation of …
[HTML][HTML] Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs
Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians
that include important vertebrate cell and developmental model systems, notably the genus …
that include important vertebrate cell and developmental model systems, notably the genus …