User profiles for O. Harismendy
 | Olivier HarismendyUC San Diego Verified email at ucsd.edu Cited by 9728 |
[HTML][HTML] Deciphering cell–cell interactions and communication from gene expression
E Armingol, A Officer, O Harismendy… - Nature Reviews …, 2021 - nature.com
Cell–cell interactions orchestrate organismal development, homeostasis and single-cell
functions. When cells do not properly interact or improperly decode molecular messages, …
functions. When cells do not properly interact or improperly decode molecular messages, …
[HTML][HTML] Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
G protein–coupled receptors (GPCRs) are the largest gene family of cell membrane–associated
molecules mediating signal transmission, and their involvement in key physiological …
molecules mediating signal transmission, and their involvement in key physiological …
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response
… The 5′ phosphate of acceptor probes and 3′ OH − of donor probes were ligated using
Taq DNA ligase. The ligated products were washed and eluted from the streptavidin magnetic …
Taq DNA ligase. The ligated products were washed and eluted from the streptavidin magnetic …
[HTML][HTML] Evaluation of next generation sequencing platforms for population targeted sequencing studies
O Harismendy, PC Ng, RL Strausberg, X Wang… - Genome biology, 2009 - Springer
Background Next generation sequencing (NGS) platforms are currently being utilized for
targeted sequencing of candidate genes or genomic intervals to perform sequence-based …
targeted sequencing of candidate genes or genomic intervals to perform sequence-based …
Microdroplet-based PCR enrichment for large-scale targeted sequencing
Targeted enrichment of specific loci of the human genome is a promising approach to enable
sequencing-based studies of genetic variation in large populations. Here we describe an …
sequencing-based studies of genetic variation in large populations. Here we describe an …
[HTML][HTML] Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling
Hepatocellular carcinoma (HCC) is a slowly developing malignancy postulated to evolve
from premalignant lesions in chronically damaged livers. However, it was never established …
from premalignant lesions in chronically damaged livers. However, it was never established …
[HTML][HTML] FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
…, D Morosini, JS Ross, O Harismendy… - Journal of translational …, 2016 - Springer
Background About 10–15% of adult, and most pediatric, gastrointestinal stromal tumors (GIST)
lack mutations in KIT, PDGFRA, SDHx, or RAS pathway components (KRAS, BRAF, NF1). …
lack mutations in KIT, PDGFRA, SDHx, or RAS pathway components (KRAS, BRAF, NF1). …
[PDF][PDF] iPSCORE: a resource of 222 iPSC lines enabling functional characterization of genetic variation across a variety of cell types
…, AD Arias, M Garcia, BC Nelson, O Harismendy… - Stem cell reports, 2017 - cell.com
Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful
model systems for examining how genetic variation affects biology and disease. Here we …
model systems for examining how genetic variation affects biology and disease. Here we …
Deep mining heterogeneous networks of biomedical linked data to predict novel drug–target associations
… of tree vertices to identify the vertex v j , where b 0 = r o o t and b l o g | V | = v j . … n o
m a r l i z e d C o n f i d e n c e D B S I d i , t j = c o n f i d e n c e D B S I d i , t j - M a x ( d i , · ) M a …
m a r l i z e d C o n f i d e n c e D B S I d i , t j = c o n f i d e n c e D B S I d i , t j - M a x ( d i , · ) M a …
[HTML][HTML] Genome-wide location of yeast RNA polymerase III transcription machinery
O Harismendy, CG Gendrel, P Soularue, X Gidrol… - The EMBO …, 2003 - embopress.org
RNA polymerase III (Pol III) transcribes a large set of genes encoding small untranslated
RNAs like tRNAs, 5S rRNA, U6 snRNA or RPR1 RNA. To get a global view of class III (Pol III-…
RNAs like tRNAs, 5S rRNA, U6 snRNA or RPR1 RNA. To get a global view of class III (Pol III-…