Interactions between microtubules and actin are a basic phenomenon that underlies many
fundamental processes in which dynamic cellular asymmetries need to be established and …

… On the other hand, a temperature of 550 C induces also metals phase transformation (from
LiCoO 2 to Co 3 O 4 and from Li 4 Mn 5 O 12 to LiMnO 4 ) increasing the subsequent …

Research increasingly suggests that subjective cognitive decline (SCD) in older adults, in
the absence of objective cognitive dysfunction or depression, may be a harbinger of non-…

Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease
would benefit from validated small animal models. Here, we show that transgenic mice …

Background First-line pembrolizumab monotherapy improves overall and progression-free
survival in patients with untreated metastatic non-small-cell lung cancer with a programmed …

Familial parkinsonism and dementia with cortical and subcortical Lewy bodies is uncommon,
and no genetic defect has been reported in the previously described sibships. We present …

Background—There are limited studies of stent thrombosis in the modern era of second-generation
stents, high-pressure deployment, and current antithrombotic regimens. Methods …

The incomplete identification of structural variants (SVs) from whole-genome sequencing
data limits studies of human genetic diversity and disease association. Here, we apply a suite …

Small-molecule inhibitors of the CDK4/6 cell-cycle kinases have shown clinical efficacy in
estrogen receptor (ER)-positive metastatic breast cancer, although their cytostatic effects are …

There is a strong rationale to therapeutically target the phosphatidylinositol 3-kinase/protein
kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway in breast cancer since …