mothur aims to be a comprehensive software package that allows users to use a single piece
of software to analyze community sequence data. It builds upon previous tools to provide a …

Rapid advances in sequencing technology have changed the experimental landscape of
microbial ecology. In the last 10 years, the field has moved from sequencing hundreds of 16S …

Although copious qualitative information describes the members of the diverse microbial
communities on Earth, statistical approaches for quantifying and comparing the numbers and …

The advent of next generation sequencing has coincided with a growth in interest in using
these approaches to better understand the role of the structure and function of the microbial …

▪ Abstract Uncultured microorganisms comprise the majority of the planet's biological diversity.
Microorganisms represent two of the three domains of life and contain vast diversity that is …

Microbial communities carry out the majority of the biochemical activity on the planet, and
they play integral roles in processes including metabolism and immune homeostasis in the …

… Reproducible research practices serve as quality checks in the process of publication and
further transparency and knowledge sharing, as detailed in the rubric proposed by Schloss 38 …

… Here Tao Ding and Patrick Schloss incorporate additional data collected over the course
of 12–18 months, partitioning the complete data set into community types for each body site …

In spite of technical advances that have provided increases in orders of magnitude in
sequencing coverage, microbial ecologists still grapple with how to interpret the genetic diversity …

Rationale: Results from 16S rDNA-encoding gene sequence–based, culture-independent
techniques have led to conflicting conclusions about the composition of the lower respiratory …