User profiles for P. Hulpiau
Paco HulpiauHowest, University College West Flanders Verified email at howest.be Cited by 4028 |
Molecular evolution of the cadherin superfamily
P Hulpiau, F Van Roy - The international journal of biochemistry & cell …, 2009 - Elsevier
This review deals with the large and pleiotropic superfamily of cadherins and its molecular
evolution. We compiled literature data and an in-depth phylogenetic analysis of more than …
evolution. We compiled literature data and an in-depth phylogenetic analysis of more than …
Mx proteins: antiviral gatekeepers that restrain the uninvited
Fifty years after the discovery of the mouse Mx1 gene, researchers are still trying to understand
the molecular details of the antiviral mechanisms mediated by Mx proteins. Mx proteins …
the molecular details of the antiviral mechanisms mediated by Mx proteins. Mx proteins …
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
… that only the N-terminal domain of ZEB1 can bind the acyltransferases p300 and P/CAF.
The functions of both p300 and P/CAF in this complex are dual. On one hand, interaction with …
The functions of both p300 and P/CAF in this complex are dual. On one hand, interaction with …
[PDF][PDF] MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
…, R Roelandt, A Goncalves, I Bruggeman, P Hulpiau… - Cell reports, 2014 - cell.com
… Accordingly, we found that inhibiting the formation of PI(5)P and PI(4,5)P2 specifically … for
the production of most intracellular PI(5)P, efficiently inhibited TNF-induced necroptosis in both …
the production of most intracellular PI(5)P, efficiently inhibited TNF-induced necroptosis in both …
Mutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathy
…, K Tyberghein, P Hulpiau… - European heart …, 2013 - academic.oup.com
… Yeast two-hybrid and cell transfection studies showed that the interaction between the p.V94D
mutant protein and β-catenin was affected, whereas the p.del765L mutant protein showed …
mutant protein and β-catenin was affected, whereas the p.del765L mutant protein showed …
[PDF][PDF] Passenger mutations confound interpretation of all genetically modified congenic mice
Targeted mutagenesis in mice is a powerful tool for functional analysis of genes. However,
genetic variation between embryonic stem cells (ESCs) used for targeting (previously almost …
genetic variation between embryonic stem cells (ESCs) used for targeting (previously almost …
Evolution and diversity of cadherins and catenins
Cadherin genes encode a superfamily of conserved transmembrane proteins that share an
adhesive ectodomain composed of tandem cadherin repeats. More than 100 human …
adhesive ectodomain composed of tandem cadherin repeats. More than 100 human …
[PDF][PDF] Formin is associated with left-right asymmetry in the pond snail and the frog
While components of the pathway that establishes left-right asymmetry have been identified
in diverse animals, from vertebrates to flies, it is striking that the genes involved in the first …
in diverse animals, from vertebrates to flies, it is striking that the genes involved in the first …
An evolutionary perspective on the necroptotic pathway
Throughout the animal kingdom, innate immune receptors protect the organism from microbial
intruders by activating pathways that mediate inflammation and pathogen clearance. …
intruders by activating pathways that mediate inflammation and pathogen clearance. …
ConTra v3: a tool to identify transcription factor binding sites across species, update 2017
Transcription factors are important gene regulators with distinctive roles in development, cell
signaling and cell cycling, and they have been associated with many diseases. The ConTra …
signaling and cell cycling, and they have been associated with many diseases. The ConTra …