A highly virulent variant of HIV-1 circulating in the Netherlands

…, B Gunsenheimer-Bartmeyer, HF Günthard, P Kivelä… - Science, 2022 - science.org
We discovered a highly virulent variant of subtype-B HIV-1 in the Netherlands. One hundred
nine individuals with this variant had a 0.54 to 0.74 log 10 increase (ie, a ~3.5-fold to 5.5-…

Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver

…, HF Günthard, P Kivelä… - Virus …, 2018 - academic.oup.com
Studying the evolution of viruses and their molecular epidemiology relies on accurate viral
sequence data, so that small differences between similar viruses can be meaningfully …

[HTML][HTML] Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

…, HF Günthard, P Kivelä… - PLoS …, 2017 - journals.plos.org
… Entropy at a position was calculated as −Σ i ∈ {A,C,G,T} p i log(p i ), and we show the
average entropy over 200-bp windows. The data used in the figure are provided as S1 Data. …

Emergency peripartum hysterectomy: results from the prospective Nordic Obstetric Surveillance Study (NOSS)

…, P Ojalainen, A Saranen, P Kivelä… - Acta obstetricia et …, 2015 - Wiley Online Library
Objective To assess the prevalence and risk factors of emergency peripartum hysterectomy.
Design Nordic collaborative study. Population 605 362 deliveries across the five Nordic …

Switching from tenofovir disoproxil fumarate to tenofovir alafenamide significantly worsens the lipid profile in a real-world setting

KJ Kauppinen, P Kivelä, J Sutinen - AIDS patient care and STDs, 2019 - liebertpub.com
… significant between categories optimal and severe dyslipidemia (p < 0.001), optimal and
dyslipidemia (p = 0.005), and between borderline and severe dyslipidemia (p = 0.001). …

[HTML][HTML] Cardiopulmonary resuscitation (CPR) training strategies in the times of COVID-19: a systematic literature review comparing different training methodologies

…, MEH Ong, JL Epstein, E Goralnick, PD Kivela… - Scandinavian journal of …, 2021 - Springer
… In CPR quality, the simplified CPR group performed better on CPR algorithm (p < 0.01), had
higher number and adequate chest compressions (p < 0.01), and shorter hands-off time (p < …

Dynamics of two separate but linked HIV-1 CRF01_AE outbreaks among injection drug users in Stockholm, Sweden, and Helsinki, Finland

…, K Liitsola, H Brummer-Korvenkontio, P Kivelä… - Journal of …, 2011 - Am Soc Microbiol
Detailed phylogenetic analyses were performed to characterize an HIV-1 outbreak among
injection drug users (IDUs) in Stockholm, Sweden, in 2006. This study investigated the source …

Evaluation of machine learning algorithms for improved risk assessment for Down's syndrome

A Koivu, T Korpimäki, P Kivelä, T Pahikkala… - Computers in Biology …, 2018 - Elsevier
… values and multiple of median (MoM)(1) M o M ( P a t i e n t ) = R e s u l t ( P a t i e n t ) m
e d i a n ( P a t i e n t P o p u l a t i o n ) values calculated using population specific median …

[HTML][HTML] Most women living with HIV can deliver vaginally—National data from Finland 1993–2013

I Aho, M Kaijomaa, P Kivelä, HM Surcel, J Sutinen… - PLoS …, 2018 - journals.plos.org
… deliveries (p = 0.071). For this same comparison, the rate of emergency CS declined from
14.8% to 4.1% (p = 0.013), but the rate of elective CS did not differ, 12.4% versus 13.7%. …

Unscheduled procedural sedation: a multidisciplinary consensus practice guideline

…, BS Krauss, JR Miner, S Schneider, PD Kivela… - Annals of emergency …, 2019 - Elsevier
The American College of Emergency Physicians (ACEP) organized a multidisciplinary effort
to create a clinical practice guideline specific to unscheduled, time-sensitive procedural …