We have previously reported that the loss of Arx and/or Pax4 gene activity leads to a shift in
the fate of the different endocrine cell subtypes in the mouse pancreas, without affecting the …

… In this issue of the JCI, Ravassard and colleagues report that this has finally been achieved
successfully with a multistep process that led to the generation of cells, which they termed …

Two proteins previously known as Na + -dependent phosphate transporters have been
identified recently as vesicular glutamate transporters (VGLUT1 and VGLUT2). Together, …

… Etienne Herzog,1 Gian Carlo Bellenchi,2 Christelle Gras,1 Veronique Bernard,3 Philippe
Ravassard… Grattier for technical support on electronic microscopy, P. Dreyfus for his patient and …

… and antisense lncRNAs were more often islet-specific than the entire collection of annotated
genes (p < 10 À10 ), up to >3-fold when considering only islet-specific lncRNAs (p < 2$10 …

OBJECTIVE Zinc ions are essential for the formation of hexameric insulin and hormone
crystallization. A nonsynonymous single nucleotide polymorphism rs13266634 in the SLC30A8 …

… significant enrichment relative to the null distribution of permuted counts for T2D and fasting
glycemia association P values of <0.001 (P values for these analyses are given in the text). …

… The position code index is significantly greater in RW than VR (P < 10 −7 ) whereas disto-code
index is significantly greater in VR (P < 10 −6 ). (D) Similarity of the population of 91 …

We have recently identified a third subtype of glutamate vesicular transporter (VGLUT) named
VGLUT3. In the present study, we provide a detailed account of the regional and cellular …

Spinal muscular atrophy (SMA) is the most common genetic disease leading to infant mortality.
This neuromuscular disorder is caused by the loss or mutation of the telomeric copy of …