… P. Villoslada critically reviewed and revised the manuscript, and approved the final … Villoslada
serves as a board member for Roche, Novartis, Neurotec Pharma, Bionure Farma, and as …

Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the introduction …

… Pablo Villoslada: analysis and interpretation, critical revision of the manuscript for important
intellectual content. Peter Calabresi: analysis and interpretation, critical revision of the …

Background: There is no consensus method for determining progression of disability in patients
with multiple sclerosis (MS) when each patient has had only a single assessment in the …

Background and objective: We explored which clinical and biochemical variables predict
conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS…

Variation in major histocompatibility complex genes on chromosome 6p21.3, specifically the
human leukocyte antigen HLA-DR2 or DRB1*1501-DQB1*0602 extended haplotype, …

Background Most patients with multiple sclerosis without previous optic neuritis have thinner
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …

… (p = 0.004). Although RNFL atrophy was greater in patients who also had optic neuritis (p
= … with controls (p = 0.014). RNFL atrophy was correlated with greater disability (r = −0.348, …

Medicine and healthcare are undergoing profound changes. Whole-genome sequencing
and high-resolution imaging technologies are key drivers of this rapid and crucial …

Objective: The clinical characteristics of patients with relapsing anti–NMDA receptor (NMDAR)
encephalitis are not well-defined. In this study, we report the clinical profile and outcome …