Genome-wide association studies (GWAS) have revealed hundreds of loci associated with
common human genetic diseases and traits. We have developed a web-based plotting tool …

By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D)
and 38,987 controls of European descent and following up previously unidentified meta-…

The genetic architecture of common traits, including the number, frequency, and effect sizes
of inherited variants that contribute to individual risk, has been long debated. Genome-wide …

Through genome-wide association meta-analyses of up to 133,010 individuals of European
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …

Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to
disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with …

LocusZoom.js is a JavaScript library for creating interactive web-based visualizations of
genetic association study results. It can display one or more traits in the context of relevant …

To the Editor—Advances in genotyping and sequencing technologies, the growing
availability of electronic health records for research use and the emergence of population-scale …

Genome-wide association studies (GWAS) have identified >100 independent SNPs that
modulate the risk of type 2 diabetes (T2D) and related traits. However, the pathogenic …

Metal–organic frameworks (MOFs) are promising high surface area coordination polymers
with tunable pore structures and functionality; however, a lack of good size and morphological …

Vaccines have an innate tendency to lose their structural conformation upon environmental
and chemical stressors. A loss in conformation reduces the therapeutic ability to prevent the …